Protein Alignment CG4607 and SLC2A14

DIOPT Version :10

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 123/490 - (25%)
• Similarity: 212/490 - (43%)
• Gaps: 70/490 - (14%)

  Fly    48 MVFLGNSGVLGSGM------VVSMPAVTLNQLHDETQPFWLNKDESS------WFASIQNMACPL 100
            ::|......:||..      |::.|...:.:..::|.....|...|.      |..|:...:  :
Human    49 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFS--V 111

  Fly   101 GGLLVSY----FLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGM 161
            ||::.|:    |::|.||::::|:.||:...|..|:....:....:|    ::|||...|:..|:
Human   112 GGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEM----LILGRLVIGLFCGL 172

  Fly   162 FVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNIQLIFGISCCYQLAATLLV 226
            ....|.:|..|||...:||.......||:..|||:....|      ::||.|....:.:.....:
Human   173 CTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFG------LELILGSEELWPVLLGFTI 231

  Fly   227 FP----------MPESPSWLL-TRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADAS 280
            .|          .||||.:|| .|.|||.|.:.|:...|......| :.|.:.|.|.|.:....
Human   232 LPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQD-IQEMKDESARMSQEKQV- 294

  Fly   281 NTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLG 345
                   ::.::.......:|:::.......||..|:..:..|:..|.:.|||. .|:...:..|
Human   295 -------TVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-QPIYATISAG 351

  Fly   346 VARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTL---HW--LPVACIVA 405
            |...|.||....:.|:.||:...:....||..|..|:        |:..|   |:  :...||.|
Human   352 VVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLM--------TVSLLLKNHYNGMSFVCIGA 408

  Fly   406 HIVFST---MGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFA 467
            .:||..   :|...:|:|:::|:|.|..|.:|..:|........|::..::|:....|| |.:|.
Human   409 ILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLG-AYVFI 472

  Fly   468 FYAG--ISFLAAAFIGVFVPETRGRTLEELEERWQ 500
            .:.|  |:|||..|..  ||||||||.|::...::
Human   473 IFTGFLITFLAFTFFK--VPETRGRTFEDITRAFE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS_GLUT6_8_Class3_like	47..494	CDD:340916	122/482 (25%)
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	119/476 (25%)