DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	522	Identity:	128/522 - (24%)
Similarity:	218/522 - (41%)	Gaps:	90/522 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GEGRLAVLRQE--------------LMVFLGNSGVLGSGM-VVSMPAVTLNQLHDET------QP 79
            |.|.|:|..|:              |:...|:|.:.|..: ||:.|...:...::.|      ||
Mouse    17 GPGELSVGHQQRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQP 81

  Fly    80 FWLNKDESSWFASIQNMACPLGGLLVSYFLDRI----GRKHTILLTNLIGLIGWILLVTSFMHSD 140
              ::.|..:...|:......:|||:.:..:..|    |||.|:|:.|...:...:|:..|.
Mouse    82 --IDPDTLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMACSL---- 140

  Fly   141 RDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR 205
            |...:..:::||...|:..|:.:|.:.:|..|||..:|||      |||..:.|.:  |:|.|..
Mouse   141 RAGTFEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRG------SLGQVTAIFI--CIGVFSG 197

  Fly   206 HNIQL------------IFG---ISCCYQLAATLLVFPMPESPSWLLTRGKEER-ARKSLRYFRG 254
            ..:.|            :||   :....|||:  |.| :||||.:||....:|. |.|:.:.|.|
Mouse   198 QLLGLPELLGRESTWPYLFGVIIVPALVQLAS--LPF-LPESPRYLLFEKHDEAGAMKAFQTFLG 259

  Fly   255 LPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVV 319
                :.|...|.|..||..:...:....     |:.:::..|.|...|:.:.......|.||:..
Mouse   260 ----KADVSQELEEALAESRVQRNLRLV-----SVLELLRAPFVRWQVITVIITMASYQLCGLNA 315

  Fly   320 IIVYAVQIAQQAGVTIDPV-LVAVMLGVARIITTLFMSGIFEKWGRKP--------SGIFSATGM 375
            |..|...|..:||:..|.: .:.:..|....:..:|...:.|:.||:|        ..:|..| :
Mouse   316 IWFYTNSIFGKAGIPQDKIPYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGT-L 379

  Fly   376 GACMLLLAGGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIF 440
            .|.:.|.....|.|       :|.:.||:|.|.....|...:||.:..|.|.|..|.:|..||..
Mouse   380 TATLTLQDQAPWVP-------YLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGT 437

  Fly   441 FGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFS 505
            ...:..|.:..::|.::.:| .:..|..:|.|....|.:....:|||:.||..|:.:     .|:
Mouse   438 VNWLSNFAVGLLFPFIQKSL-DSYCFLVFATICIAGATYFYFVLPETKNRTHAEISQ-----AFA 496

  Fly   506 RR 507
            :|
Mouse   497 KR 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	112/464 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	113/462 (24%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	120/485 (25%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834437
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840