DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and slc2a11l2

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001339155.2	Gene:	slc2a11l2 / 110386950	-ID:	-	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	491	Identity:	110/491 - (22%)
Similarity:	206/491 - (41%)	Gaps:	90/491 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 VVSMPAVTLNQLHDETQPFWLNKDESS---------W--FASIQNMACPLGGLLVSYFLDRIGRK 115
            |::.|:..:.|..:|:   |:.:.|::         |  ..|:.::.|.:|.:...|...::|:|
Frog    35 VLNSPSPFIKQFINES---WMRRHETTITQGTHTLIWSLTVSVFSIGCLIGSVSSGYLSGKLGKK 96

  Fly   116 HTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRG 180
            ..:|....:.||..:|:..    |....::..:::||...||.:|:.::....|..|.:..|:.|
Frog    97 KCMLYNTFLPLINTVLMGL----SQTVGLFELIIVGRFLCGIYVGLGLNIHAQYIGESAPRKLLG 157

  Fly   181 RL--------ILGTSLGLASGILLMYCLGYFIRHNIQLIF-------GISCCYQLAATLLVFPMP 230
            .|        .||...|...||..::        ..:|::       ||:...|| .||.:|  |
Frog   158 FLNCLAPMFVTLGKLCGQIVGIRELF--------GTELMWPYILVPSGITSLVQL-ITLPLF--P 211

  Fly   231 ESPSWLL-TRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIH 294
            |:|.:|| .:|.:|...|:|:...|    :.|:..|.| |:...:.....:......|.|....|
Frog   212 ETPHYLLQVKGDKEACVKALKQLWG----DRDHQAEIE-EMIEQQRAQKKTGNMGILELLKDPSH 271

  Fly   295 RPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPV-LVAVMLGVARIITTLFMSGI 358
            |.::|..:.::.|    .|..|...|..|:..:.:.|....|.: .|::.:|....::.:..|.:
Frog   272 RWQLYSMIGLILT----MQLSGANAIYFYSYDVFRAANFPPDKISYVSIGVGAFEFVSAMVCSLL 332

  Fly   359 FEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLH----------WLPVACIVAHIVFSTM- 412
            .|.:|||             .|:|.|.:.....||.|.          |:|. |.|| :|||.:
Frog   333 IEHFGRK-------------FLMLGGFSLMSLILGLLTVTLSLQDSYLWMPY-CSVA-LVFSFIF 382

  Fly   413 ----GMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAF--YAG 471
                |.....|....|:|.|..|..|..::..|..:..:|:..|:|.:   :||...|.|  :..
Frog   383 VFGAGPAGSIFTTCVEIFAQAPRVPALAVSGVFSWVGLYILGMIFPYL---VGTLGHFCFLLFIA 444

  Fly   472 ISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRR 507
            :..:::......||||:|:::.::.:.:....|.|:
Frog   445 VMLISSTLAFFIVPETKGKSIAQISQEFNKFNFRRQ 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	103/466 (22%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	106/472 (22%)
slc2a11l2	NP_001339155.2	MFS	17..468	CDD:421695	108/477 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910