DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and slc2a11.2

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001339156.1	Gene:	slc2a11.2 / 100496725	XenbaseID:	XB-GENE-5857129	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	519	Identity:	129/519 - (24%)
Similarity:	222/519 - (42%)	Gaps:	92/519 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GRLAVLRQELMVFLGNSGVLGSGMVVSM---PAVTLNQ-------------LH-DETQPFWLNKD 85
            |:|.:....|.:.||..|....|:.:|:   ||..:.:             || |:...||
Frog     8 GKLTLNLTLLCLVLGIGGTFQYGLHISLINSPAEYIQKFINDTWQHRYGSPLHPDKITLFW---- 68

  Fly    86 ESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLL 150
              |:..|:.::...:|.|:|.|.....|||.|.|..|:..|:|..|::.|.:....:||    ::
Frog    69 --SFIVSVYSIGGLMGSLIVGYLSVSFGRKKTQLYNNVFALLGAALMMLSPVAQSFEMI----IV 127

  Fly   151 GRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNIQLIFGIS 215
            ||...|:..|:.::...:|..|.:..|:|| :.:..||.:|.|.|:.:.:|      ::...|..
Frog   128 GRFLYGVNTGVSLNLHTMYIGECAPKKLRG-ISVTVSLFIALGKLMGFVVG------LREFLGSE 185

  Fly   216 CCYQLAAT---------LLVFP-MPESPSWLL-TRGKEERARKSLRYFRGLPKKEVDYVPEFEAE 269
            ..:....:         ||..| .||||.:|| .:..:|...|:::...|..    |:|.|.:..
Frog   186 ALWPYLMSFSAVPALVQLLTLPFFPESPRYLLIDKDNKEGCLKAMQQLWGAG----DHVAEMDDM 246

  Fly   270 LAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVT 334
            ||....| :........:.|.:...|.::...||..    |..|..|:.|:..||..:.:.||:.
Frog   247 LAEKNSL-EGEQRKGVMDLLKKRCVRWQMISIVLTC----GAIQLTGINVVYFYAYDVFRNAGIP 306

  Fly   335 IDPV-LVAVMLGVARIITTLFMSGIFEKWGRKP-----SGIFSATGMGACMLLLAGGNWFPDTLG 393
            ...: .:::.:||...:||:....:.::.||||     .|:.:.|    ..||.|     ..:|.
Frog   307 DRQIPFISLGIGVTEALTTVLCGFVIDRMGRKPLLWINYGVITLT----LSLLTA-----TLSLQ 362

  Fly   394 TLH-WLPVACIVAHIVFSTMGMLTLPF---------FMISEVFPQRARGSA---SGIAIFFGMIL 445
            .|| |:|........:|      ||.|         .:.:|:|.|..|.:|   .||..:.||
Frog   363 DLHSWMPYFSSALIFIF------TLSFGLGPGGVSCVIPTEMFVQSYRPAAYMLIGILNWLGM-- 419

  Fly   446 AFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRRLT 509
             ||:...:|.|||||| |..|.|:..:......|..:.:|||:.:::.|:.:.:....|.::.|
Frog   420 -FILAWSFPFMEAALG-AFCFVFFIILCICMGIFSFLILPETKNKSILEILDSFNQLNFRQQKT 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	118/475 (25%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	117/471 (25%)
slc2a11.2	NP_001339156.1	MFS	22..467	CDD:391944	122/489 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910