DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4593 and ccdc25

DIOPT Version :9

Sequence 1:	NP_001284975.1	Gene:	CG4593 / 31649	FlyBaseID:	FBgn0029929	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_001004803.1	Gene:	ccdc25 / 448037	XenbaseID:	XB-GENE-5887637	Length:	206	Species:	Xenopus tropicalis

Alignment Length:	210	Identity:	125/210 - (59%)
Similarity:	167/210 - (79%)	Gaps:	5/210 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTD 65
            |||||.|||:.||..:|||:||:|||:||::|||||:||||..||||||||||:|.|||:|||.:
Frog     1 MVFYFTSNVISPPYTMYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKDQTIEDIPKE 65

  Fly    66 VLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVN 130
            ||:|.|||.|||||||.|:||:.||||.|.|||||.||:.||:.:|.:|.|:.:.:|| :::|||
Frog    66 VLLDCAQLVKANSIQGCKMNNINVVYTPWANLKKTADMDIGQIGFHRQKDVKTMTVEK-VSKIVN 129

  Fly   131 RLNRTKTEEEHPDFRGLREARDAAERQDQK-KIQRERREQEKEAAKQRELEAELRSYASLQKSEN 194
            ||.:|| :|..||....:||||..||.::| :||..:|::::|..|::|:: |||||:||.||||
Frog   130 RLEKTK-DERFPDLAAEKEARDREERNEKKAQIQEIKRKEKEEMKKKKEMD-ELRSYSSLMKSEN 192

  Fly   195 MRTNYDAGNESDDFM 209
            |.:|.| ||:|||||
Frog   193 MSSNQD-GNDSDDFM 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4593	NP_001284975.1	DUF814	7..99	CDD:283353	64/91 (70%)
CG4593	NP_001284975.1	DUF4337	<123..>182	CDD:290935	24/59 (41%)
ccdc25	NP_001004803.1	DUF814	1..111	CDD:398994	76/109 (70%)
		DNA-binding. /evidence=ECO:0000250\|UniProtKB:Q86WR0	20..24		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..206		34/68 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3667
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6645
Inparanoid	1	1.050	251	1.000	Inparanoid score	I3138
OMA	1	1.010	-	-		QHG53870
OrthoDB	1	1.010	-	-		D1380409at2759
OrthoFinder	1	1.000	-	-		FOG0004988
OrthoInspector	1	1.000	-	-		oto102978
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2167
SonicParanoid	1	1.000	-	-		X3521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010