DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4593 and ccdc25

DIOPT Version :9

Sequence 1:	NP_001284975.1	Gene:	CG4593 / 31649	FlyBaseID:	FBgn0029929	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_956682.1	Gene:	ccdc25 / 393359	ZFINID:	ZDB-GENE-040426-1389	Length:	207	Species:	Danio rerio

Alignment Length:	210	Identity:	121/210 - (57%)
Similarity:	164/210 - (78%)	Gaps:	4/210 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTD 65
            |||||.|.||.||..:|||:||:|||:||::|||||:||||..|||||||||:.||.||||||.:
Zfish     1 MVFYFTSAVVSPPHTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGTTIDDIPKE 65

  Fly    66 VLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVN 130
            ||:|..||.|.|||||.|:||:.:|||.|.|||||.||:.||:.:|.:|.|:.:.:||:||||||
Zfish    66 VLIDCVQLVKNNSIQGCKMNNINIVYTPWSNLKKTADMDIGQIGFHRQKEVKIVAVEKKINEIVN 130

  Fly   131 RLNRTKTEEEHPDFRGLREARDAAERQDQK-KIQRERREQEKEAAKQRELEAELRSYASLQKSEN 194
            ||.:|| ||.:||....:|:||..||.::| :||.:::::::|..|::|:| :|::|.||.||:|
Zfish   131 RLEKTK-EERYPDLAAEKESRDREERNEKKAQIQEQKKKEKEEVKKKKEME-DLKNYTSLMKSDN 193

  Fly   195 MRTNYDAGNESDDFM 209
            |.||.| |.:|||||
Zfish   194 MTTNED-GYDSDDFM 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4593	NP_001284975.1	DUF814	7..99	CDD:283353	61/91 (67%)
CG4593	NP_001284975.1	DUF4337	<123..>182	CDD:290935	27/59 (46%)
ccdc25	NP_956682.1	DUF814	4..99	CDD:283353	63/94 (67%)
		DNA-binding. /evidence=ECO:0000250\|UniProtKB:Q86WR0	20..24		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..207		29/68 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595517
Domainoid	1	1.000	167	1.000	Domainoid score	I3818
eggNOG	1	0.900	-	-		E1_KOG3272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6645
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3202
OMA	1	1.010	-	-		QHG53870
OrthoDB	1	1.010	-	-		D1380409at2759
OrthoFinder	1	1.000	-	-		FOG0004988
OrthoInspector	1	1.000	-	-		oto39596
orthoMCL	1	0.900	-	-		OOG6_102835
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2167
SonicParanoid	1	1.000	-	-		X3521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.700