DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4593 and Y54G11A.2

DIOPT Version :9

Sequence 1:	NP_001284975.1	Gene:	CG4593 / 31649	FlyBaseID:	FBgn0029929	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_496971.1	Gene:	Y54G11A.2 / 175082	WormBaseID:	WBGene00013213	Length:	210	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	108/211 - (51%)
Similarity:	143/211 - (67%)	Gaps:	3/211 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTD 65
            ||..|.||...||.|:|||.||.|||:||::||||||||||..||||||||||..|.|||.||..
Worm     1 MVIKFSSNTTNPPTMIYMGVDKVENEDLIKYGWPEDVWFHVDKLSSAHVYLRLHSGMTIDSIPEA 65

  Fly    66 VLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVN 130
            :|:|..||.|.|||:|.|:||:.:|||||.|||||.||..|||.:|:.|.|:...:..:||||||
Worm    66 LLIDCCQLVKQNSIEGCKLNNVAIVYTMWSNLKKTGDMAVGQVGFHSHKQVKHTVVPTKINEIVN 130

  Fly   131 RLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASL--QKSE 193
            ||.:|:.::: .|::..|:||||.|||..||:::||:::||:....:..:..:..|..:  ....
Worm   131 RLEKTRRKDD-IDYKEERDARDAKERQKLKKLEQERKDREKKEMLAQNEKKRIEGYEDVDWDAGA 194

  Fly   194 NMRTNYDAGNESDDFM 209
            ..|.:.|.||.|||||
Worm   195 TTRNDVDPGNLSDDFM 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4593	NP_001284975.1	DUF814	7..99	CDD:283353	60/91 (66%)
CG4593	NP_001284975.1	DUF4337	<123..>182	CDD:290935	24/58 (41%)
Y54G11A.2	NP_496971.1	DUF814	15..111	CDD:368552	64/95 (67%)
Y54G11A.2	NP_496971.1	Selenoprotein_S	<88..>173	CDD:369143	42/85 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166967
Domainoid	1	1.000	157	1.000	Domainoid score	I2548
eggNOG	1	0.900	-	-		E1_KOG3272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6645
Inparanoid	1	1.050	218	1.000	Inparanoid score	I2309
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53870
OrthoDB	1	1.010	-	-		D1380409at2759
OrthoFinder	1	1.000	-	-		FOG0004988
OrthoInspector	1	1.000	-	-		oto20099
orthoMCL	1	0.900	-	-		OOG6_102835
Panther	1	1.100	-	-	LDO	PTHR13049
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2167
SonicParanoid	1	1.000	-	-		X3521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800