Protein Alignment CG3032 and ZNF665

DIOPT Version :10

• Sequence 1: NP_572376.1
• Gene: CG3032 / 31648
• FlyBaseID: FBgn0029928
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001340387.1
• Gene: ZNF665 / 79788
• HGNCID: 25885
• Length: 706
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 117/482 - (24%)
• Similarity: 205/482 - (42%)
• Gaps: 114/482 - (23%)

  Fly    30 LQSDEIPISQELQQLLNINLSQDVENQDADQQWLPNELCLECRSAVQNFEKFRR----------- 83
            ||.:.:| .:..|:          :.:.|..:.:.|:|.:..:|.:...::|:.
Human   143 LQKENLP-GRRAQR----------DRRAAGNRHIENQLGVSFQSHLPELQQFQHEGKIYEYNQVE 196

  Fly    84 ----------KADECRKQLLEMLKKDPREPTFEVVYDGREEDQ-----------------ESLHG 121
                      |.|||.|    :..::.|..:.:.::.|.:..|                 :.:|.
Human   197 KSPNNRGKHYKCDECGK----VFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTIHQVIHT 257

  Fly   122 LEPPEPAPDPDPI-DEPA-------IKSDKSP------RKSFRG------------SRNTLKCSV 160
            .|.|....:...: .:|:       |.:.:.|      .|:||.            .....||..
Human   258 GEKPYKCNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKE 322

  Fly   161 CRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPGCER 225
            |.:.|.....||:| |::|.|.| |::|::|.||:|....|.|| :.:|. .|:.:.|::  |.:
Human   323 CGKCFTQNSHLASH-RRIHTGEK-PYKCNECGKAFSVRSSLTTH-QTIHT-GEKPYKCNE--CGK 381

  Fly   226 IYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREG---- 286
            ::.....:.||:|: |:..     |.:.|.:||.:|:..:||..| :..|..|......|.
Human   382 VFRHNSYLAKHRRI-HTGE-----KPYKCNECGKAFSMHSNLTKH-QIIHTGEKPFKCNECVKVF 439

  Fly   287 ------------GAGERHF-CDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFML 338
                        ..||:.: ||.|.|.|..|.:|..|   |.....|.|::|..||:...:...|
Human   440 TQYSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTH---QAIHTGEKPYKCNDCGKVFTQNSHL 501

  Fly   339 LQHMLMHSNDK-LPCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHT 402
            ..|..:||.:| ..|:.||:.|::..:|..|.| ||...||:.|:.|.::|:...:|..|:.|||
Human   502 ASHRGIHSGEKPYKCDECGKAFSQTSQLARHWR-VHTGEKPYKCNECGKAFSVHSSLTIHQTIHT 565

  Fly   403 GEKPYICDTCGQAFRQQTCLKNHRKVH 429
            |:|||.|:.||:.||..:.|..|:::|
Human   566 GQKPYKCNDCGKVFRHNSYLAIHQRIH 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_572376.1	zf-AD	13..95	CDD:462262	14/85 (16%)
		C2H2 Zn finger	158..179	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..209	CDD:275368	8/20 (40%)
		SFP1	<213..275	CDD:227516	15/61 (25%)
		C2H2 Zn finger	218..239	CDD:275368	4/20 (20%)
		C2H2 Zn finger	254..275	CDD:275368	7/20 (35%)
		C2H2 Zn finger	294..315	CDD:275368	8/20 (40%)
		C2H2 Zn finger	325..345	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
ZNF665	NP_001340387.1	KRAB	37..76	CDD:460171
		COG5048	192..580	CDD:227381	103/408 (25%)
		C2H2 Zn finger	208..228	CDD:275368	5/23 (22%)
		C2H2 Zn finger	236..256	CDD:275368	0/19 (0%)
		C2H2 Zn finger	264..284	CDD:275368	1/19 (5%)
		C2H2 Zn finger	292..312	CDD:275368	3/19 (16%)
		C2H2 Zn finger	320..340	CDD:275368	7/20 (35%)
		C2H2 Zn finger	348..368	CDD:275368	8/20 (40%)
		C2H2 Zn finger	376..396	CDD:275368	5/22 (23%)
		C2H2 Zn finger	404..424	CDD:275368	7/20 (35%)
		C2H2 Zn finger	432..452	CDD:275368	1/19 (5%)
		C2H2 Zn finger	460..480	CDD:275368	9/22 (41%)
		C2H2 Zn finger	488..508	CDD:275368	5/19 (26%)
		C2H2 Zn finger	516..536	CDD:275368	7/20 (35%)
		C2H2 Zn finger	544..564	CDD:275368	5/19 (26%)
		C2H2 Zn finger	572..592	CDD:275368	7/19 (37%)
		zf-H2C2_2	584..608	CDD:463886	3/9 (33%)
		C2H2 Zn finger	600..620	CDD:275368
		zf-H2C2_2	612..637	CDD:463886
		C2H2 Zn finger	628..648	CDD:275368
		zf-H2C2_2	640..664	CDD:463886
		C2H2 Zn finger	656..676	CDD:275368
		zf-H2C2_2	669..693	CDD:463886
		C2H2 Zn finger	684..704	CDD:275368