DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and si:ch211-222k6.2

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001373745.1	Gene:	si:ch211-222k6.2 / 556142	ZFINID:	ZDB-GENE-030131-9038	Length:	364	Species:	Danio rerio

Alignment Length:	330	Identity:	95/330 - (28%)
Similarity:	147/330 - (44%)	Gaps:	46/330 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 EVVYDGREEDQESLHGLEPPEPAPDPDPIDEPAIKSDKSPRKSFRGSRNT-LKCSVCRRSFAHQI 169
            |.:.|..||::::...||..|...|        ....||...||:..... ..|..|.:||:...
Zfish    15 EELIDLMEENRQTGELLEAVEKHQD--------THGQKSMSPSFQSRPEVHFTCPQCGKSFSCDQ 71

  Fly   170 TLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPGCERIYTSRIAMQ 234
            :|..|: |.|.|:| |:.||||:|.::....|..|:: :|..| ..:.|.|  |..|:|....:.
Zfish    72 SLNLHM-KFHRGTK-PYACDQCDKIFTLKTNLNEHMK-IHTAK-MLYTCGQ--CGTIFTDEGNLN 130

  Fly   235 KHKR--LKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHF-CDI 296
            :|.:  :...|        |.|..||..|....|...|:|..             .|||.: ||.
Zfish   131 EHMKSHVVEMP--------FTCGHCGKRFTYKGNFNEHMKIH-------------TGERPYACDQ 174

  Fly   297 CQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDKLP--CEHCGRRF 359
            |.|.|..:..|..|.:..   ..|.||.|..||::...|.:|..||.:|:.: :|  |:.||..|
Zfish   175 CGKRFTHKGNLNKHIIVH---TGEKPHSCDQCGKKFKLKHILNDHMKIHTGE-MPYMCDQCGTSF 235

  Fly   360 ARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCLKN 424
            .:......|:| .|..::||.|..|.:.|.:...|::|..:|...||::|..||::|.:.:.||.
Zfish   236 RKLDTFRLHLR-YHSGVRPFSCDQCGKHFFTSVALKYHVKVHAKVKPHVCSLCGKSFMELSGLKK 299

  Fly   425 HRKVH 429
            |:|.|
Zfish   300 HQKRH 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..209	CDD:275368	7/20 (35%)
		C2H2 Zn finger	218..239	CDD:275368	6/22 (27%)
		C2H2 Zn finger	254..275	CDD:275368	7/20 (35%)
		C2H2 Zn finger	294..315	CDD:275368	7/20 (35%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	8/19 (42%)
si:ch211-222k6.2	NP_001373745.1	C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		C2H2 Zn finger	172..192	CDD:275368	7/19 (37%)
		C2H2 Zn finger	200..220	CDD:275368	7/19 (37%)
		C2H2 Zn finger	228..248	CDD:275368	6/20 (30%)
		C2H2 Zn finger	256..276	CDD:275368	5/19 (26%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		C2H2 Zn finger	312..332	CDD:275368
		C2H2 Zn finger	340..360	CDD:275368
		COG5048	37..>362	CDD:227381	88/308 (29%)
		C2H2 Zn finger	60..80	CDD:275368	7/20 (35%)
		C2H2 Zn finger	88..108	CDD:275368	7/20 (35%)
		C2H2 Zn finger	116..136	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12262
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000