DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and Aef1

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	72/294 - (24%)
Similarity:	112/294 - (38%)	Gaps:	80/294 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 QITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRH---------PCDQPGC 223
            |.|..||:..|.:..::..|..|                :.|..::::.         |.:.|..
  Fly    45 QATHPAHMAAVQQQQQQQQQQQQ----------------QHHQQQQQQSSGPPSVPPPPTELPLP 93

  Fly   224 ERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQS--------ANLKYHLKT------- 273
            .:::.|.|:.:.|...:.:..   |..:....|..|:..|.        .:|..|..|
  Fly    94 FQMHLSGISAEAHSAAQAAAM---AAAQAAAAQAAAAEQQQPPPPTSHLTHLTTHSPTTIHSEHY 155

  Fly   274 ------KHPTEDEVAAREGGAGERHFCDICQKEFHSRYTLKYHTLQQHEVQE-ELPHECQVCGRR 331
                  :||.|...|...|||                            |:| |.|..|.||.||
  Fly   156 LANGHSEHPGEGNAAVGVGGA----------------------------VREPEKPFHCTVCDRR 192

  Fly   332 MAKKFMLLQHMLMHSNDK-LPCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLR 395
            ..:...|..|:.:|:.:| ..|..|.:.|.:...|..|:: :|...||:.|:.||:.|....||.
  Fly   193 FRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLK-IHTGEKPYNCNFCPKHFRQLSTLA 256

  Fly   396 HHEYIHTGEKPYICDTCGQAFRQQTCLKNHRKVH 429
            :|..|||||||:.|..|.:.|||.:.|.||.|:|
  Fly   257 NHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIH 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	4/10 (40%)
		C2H2 Zn finger	188..209	CDD:275368	1/20 (5%)
		C2H2 Zn finger	218..239	CDD:275368	4/20 (20%)
		C2H2 Zn finger	254..275	CDD:275368	6/41 (15%)
		C2H2 Zn finger	294..315	CDD:275368	0/20 (0%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
		C2H2 Zn finger	381..401	CDD:275368	7/19 (37%)
		C2H2 Zn finger	409..429	CDD:275368	9/19 (47%)
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	7/19 (37%)
		zf-H2C2_2	199..223	CDD:290200	7/23 (30%)
		C2H2 Zn finger	214..234	CDD:275368	5/20 (25%)
		zf-H2C2_2	227..251	CDD:290200	9/24 (38%)
		C2H2 Zn finger	242..262	CDD:275368	7/19 (37%)
		zf-H2C2_2	255..279	CDD:290200	12/23 (52%)
		C2H2 Zn finger	270..290	CDD:275368	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	42	1.000	Inparanoid score	I2696
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050