DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and CG10654

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	97/426 - (22%)
Similarity:	161/426 - (37%)	Gaps:	129/426 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LCCTCLLQLEKEPLKTELQSDEIPISQELQQLLNINLSQDVENQDADQQWLPNELCLECRSAVQN 77
            :|..||:.|..:.....|.|:     |:|.........:|.. :|...|.:...:|..|...||.
  Fly    39 ICRACLVLLGPQDACHNLDSE-----QDLASKYYGCTGEDAV-RDLPPQLVLKSICECCYQLVQK 97

  Fly    78 FEKFRRKADECRKQLLEMLKKDPREPTFEVVYDGREEDQESLHGLEPP---EPAPDPDP------ 133
            |..|:|...|..:...::|:        ::.....:.:..:.|.|:.|   ..:.:|:.
  Fly    98 FHDFQRMCAESLRNFEKLLQ--------DIDIGCHKLEDHTWHDLDTPSESNESTNPEAQSHAPC 154

  Fly   134 --------------------------------------IDEPAIKSDKSPRK-----------SF 149
                                                  |::.:.|.|....|           ..
  Fly   155 IAATQEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLSISSKLLGARKR 219

  Fly   150 RGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKER 214
            ||.|:||:|.:|.|.|.....|.||::: ||| .||:.|..|.|:|:....|.:|:|::|...:.
  Fly   220 RGVRHTLECRICHRGFYKPSLLEAHMQQ-HEG-LRPYTCVHCAKSYARANLLESHLRQMHNNADA 282

  Fly   215 R---HPCDQPGCERIYTSRIAMQKHKRLKH-------SPRDRDALKKFICEQCGASFNQSANLKY 269
            .   :.|  |.|.::||:..:::.|.|..|       ||   ||  :.|||:||..|.:.|:|..
  Fly   283 ARIIYAC--PSCNKVYTANRSLKYHMRRTHERYHESESP---DA--RHICEECGKCFARKAHLTR 340

  Fly   270 HLKTKHPTEDEVAAREGGAGERHFCDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAK 334
            | |..|.:.:         |.|:.|:.|.:.|:::..:..|.|::|                 ..
  Fly   341 H-KMVHGSVE---------GRRYCCECCDRRFYTKENMVDHLLRKH-----------------GN 378

  Fly   335 KFMLLQHMLMHSNDKLPCEHCGRRFARRFELEAHVR 370
            |.:||:           |..|||.|....||.||.|
  Fly   379 KNLLLR-----------CRKCGRIFQNSVELNAHGR 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	19/81 (23%)
		C2H2 Zn finger	158..179	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..209	CDD:275368	7/20 (35%)
		C2H2 Zn finger	218..239	CDD:275368	6/20 (30%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		C2H2 Zn finger	294..315	CDD:275368	5/20 (25%)
		C2H2 Zn finger	325..345	CDD:275368	3/19 (16%)
		C2H2 Zn finger	352..373	CDD:275368	10/19 (53%)
		C2H2 Zn finger	381..401	CDD:275368
		C2H2 Zn finger	409..429	CDD:275368
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	19/81 (23%)
		C2H2 Zn finger	228..248	CDD:275368	7/20 (35%)
		C2H2 Zn finger	256..313	CDD:275368	16/58 (28%)
		C2H2 Zn finger	289..314	CDD:275368	8/26 (31%)
		zf-C2H2	323..345	CDD:278523	10/22 (45%)
		C2H2 Zn finger	325..345	CDD:275368	9/20 (45%)
		C2H2 Zn finger	355..376	CDD:275368	5/20 (25%)
		C2H2 Zn finger	385..405	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455453
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030