DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and CG2129

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	94/395 - (23%)
Similarity:	155/395 - (39%)	Gaps:	114/395 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 REEDQESLHGLEPPEPAP-----------------DPDPIDEPAIKSDKSPRKSFRGSRNTLKCS 159
            :|.|:|.    ||..|.|                 :.|..||..:...:...:..|..|:.:|..
  Fly    73 QERDRER----EPNSPVPIVAQVNPFAWYEIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQ 133

  Fly   160 VCRRSFAHQITLAAHIRKV--------HEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRH 216
                  .||...:..:|:|        .|.|::    ::|        |:     |:....|.||
  Fly   134 ------DHQSLTSESLRQVRALKVDYKEEDSEQ----EEC--------GM-----ELDLDSEGRH 175

  Fly   217 ----PCDQPGCERIYTSRIAMQKHKRLKHS----------------PRD---RDALKKFICEQCG 258
                |...|.|.::|.||..:::|...:|.                |:|   :.|.:::.||.||
  Fly   176 SAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAAQEYKCEHCG 240

  Fly   259 ASFNQSANLKYHLKTKHPTEDE------------------------VAAREGGAGERHFCDICQK 299
            ..::...:|:.|||..|...:|                        :....|||.    |.:|.:
  Fly   241 KIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAHGGAA----CVVCGR 301

  Fly   300 EFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHM----LMHSNDK-LPCEHCGRRF 359
            .:.:|:.||.|.| :|..:..:|.....||    |:|..::||    .:|:..| ..||.||...
  Fly   302 RYKTRHELKRHQL-KHTSERNVPCPHPGCG----KRFFTIRHMRNHGKVHTEQKNFVCESCGYSC 361

  Fly   360 ARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCLKN 424
            ..:..|..|:|: |...:||.|..|.:.|.|...||.|..:|:.|:|::|..||..|.:|..|.:
  Fly   362 RNKETLRVHIRS-HTGERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVCSVCGATFSRQKGLYH 425

  Fly   425 HRKVH 429
            |:.:|
  Fly   426 HKFLH 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	4/28 (14%)
		C2H2 Zn finger	188..209	CDD:275368	3/20 (15%)
		C2H2 Zn finger	218..239	CDD:275368	6/20 (30%)
		C2H2 Zn finger	254..275	CDD:275368	8/20 (40%)
		C2H2 Zn finger	294..315	CDD:275368	7/20 (35%)
		C2H2 Zn finger	325..345	CDD:275368	6/23 (26%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	7/19 (37%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	7/20 (35%)
		zf-C2H2_8	323..411	CDD:292531	29/92 (32%)
		C2H2 Zn finger	327..346	CDD:275368	6/22 (27%)
		C2H2 Zn finger	354..374	CDD:275368	7/20 (35%)
		zf-H2C2_2	367..389	CDD:290200	8/22 (36%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	10/23 (43%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930