DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3032 and Gzf1

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001101258.1	Gene:	Gzf1 / 311508	RGDID:	1562321	Length:	707	Species:	Rattus norvegicus

Alignment Length:	529	Identity:	144/529 - (27%)
Similarity:	214/529 - (40%)	Gaps:	146/529 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ESVRELCC-----TCLLQLEKEPLKT---ELQ----SDEIPISQELQ------QLLNINLSQD-- 52
            |...:|.|     || |||:|:.|::   |||    |.|:..|...|      ...::...:|
  Rat   111 EVAEKLKCLDLSETC-LQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPAGEDAH 174

  Fly    53 ----VENQDADQQWLPNELCLECRSAVQNFEKFRRKADECRKQLLEMLKKDPREPTFEVV----- 108
                |::.|...:.|.|.|..|..|     :|.:.|.|:         |||..:|.|..:
  Rat   175 SNGLVDSSDYPIERLGNGLSPETPS-----KKCKEKLDK---------KKDVAKPPFPKIRRASG 225

  Fly   109 ---------------YDGR-EEDQESLHGLE-----PPEPAPDPDPID-EPAIKSDKSPR----- 146
                           |..| .|.|:|.....     |.:.:||.:.:: |||.||:..|.
  Rat   226 RLAGKKVFVEIPKKKYTRRLREQQKSAEEAAKNDKCPQDQSPDNERVEAEPASKSEACPASVERE 290

  Fly   147 --------------------------------KSFRGSRNTLK---------------CSVCRRS 164
                                            |:|...::.||               |..|.::
  Rat   291 ESLQKVEGEKEEEEGKDGEEKKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQT 355

  Fly   165 FAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPGCERIYTS 229
            ||::..|.:|.|.|| .|:|.|.|:.|.|.:.....:..|:.:||.....||.|.|  |.:..:|
  Rat   356 FANRCNLKSHQRHVH-SSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQ--CGKGLSS 417

  Fly   230 RIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHF- 293
            :.|::.|:|.....      |.:.|.:|.|.|:|.:.||.||:..             .|||.|
  Rat   418 KTALRLHERTHTGD------KPYGCTKCDAKFSQPSALKTHLRVH-------------TGERPFV 463

  Fly   294 CDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDK-LPCEHCGR 357
            ||.|...|...:.|.||. :.|  ..|.|..|:.||:..|.|..|..|..:|:..| ..||.|.|
  Rat   464 CDECGARFTQNHMLIYHK-RCH--TGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLR 525

  Fly   358 RFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCL 422
            .||:|..|..|:: ||...:|:.|..|.:.|.....|:.|..||||||||:|:.||:.|..::.|
  Rat   526 TFAQRNSLYQHIK-VHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTL 589

  Fly   423 KNHRKVHEK 431
            :.|..:|:|
  Rat   590 RRHTSIHDK 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	27/105 (26%)
		C2H2 Zn finger	158..179	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..209	CDD:275368	4/20 (20%)
		C2H2 Zn finger	218..239	CDD:275368	6/20 (30%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		C2H2 Zn finger	294..315	CDD:275368	7/20 (35%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..373	CDD:275368	9/20 (45%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	6/19 (32%)
Gzf1	NP_001101258.1	BTB	21..125	CDD:279045	3/13 (23%)
		BTB	32..125	CDD:197585	3/13 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	149..221		18/85 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..309		13/65 (20%)
		C2H2 Zn finger	318..338	CDD:275370	4/19 (21%)
		C2H2 Zn finger	349..370	CDD:275368	7/20 (35%)
		C2H2 Zn finger	408..428	CDD:275368	7/21 (33%)
		COG5048	<411..539	CDD:227381	47/150 (31%)
		C2H2 Zn finger	436..456	CDD:275368	9/19 (47%)
		zf-H2C2_2	448..473	CDD:290200	12/37 (32%)
		C2H2 Zn finger	464..484	CDD:275368	7/20 (35%)
		zf-H2C2_2	476..501	CDD:290200	9/27 (33%)
		C2H2 Zn finger	492..512	CDD:275368	7/19 (37%)
		zf-H2C2_2	504..529	CDD:290200	9/24 (38%)
		C2H2 Zn finger	520..540	CDD:275368	9/20 (45%)
		zf-H2C2_2	532..557	CDD:290200	8/25 (32%)
		COG5048	544..>601	CDD:227381	22/55 (40%)
		C2H2 Zn finger	548..568	CDD:275368	5/19 (26%)
		zf-H2C2_2	560..584	CDD:290200	13/23 (57%)
		C2H2 Zn finger	576..596	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000