DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and Zbtb17

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001365755.1	Gene:	Zbtb17 / 22642	MGIID:	107410	Length:	819	Species:	Mus musculus

Alignment Length:	471	Identity:	124/471 - (26%)
Similarity:	197/471 - (41%)	Gaps:	111/471 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SQDVENQDADQQWLPNELCLECRSAVQNFEKFRRKADECRKQLLEMLKKDPREPTFEVVYDGREE 114
            ::..|..||.::..|.||..:..|::...|  .....|..:|.:|:......|       ||:||
Mouse   205 AEQTEKADAPREPPPVELKPDPTSSMAAAE--AEALSESSEQEMEVEPASKGE-------DGQEE 260

  Fly   115 D--------QESLH--GLEPPEPAPDPDPID------------EPAIKSDKSPRKSFRGSRNTLK 157
            :        :|.:|  ..||||...:....|            ......|::..|::....:  |
Mouse   261 EGAGPATVKEEGMHLDNGEPPEENEESAGTDSGQELGMEGQNLRSGTYGDRTESKAYGSIIH--K 323

  Fly   158 CSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPG 222
            |..|.:.|.|......||| :|.|.| ||.|.:|.||:|.......| .:.|:|. :.:.|::.|
Mouse   324 CEDCGKEFTHTGNFKRHIR-IHTGEK-PFSCRECSKAFSDPAACKAH-EKTHSPL-KPYGCEECG 384

  Fly   223 --------------------------CERIYTSRIAMQKHKRLKHS----------------PRD 245
                                      |.:::|:...:::| :|.||                |..
Mouse   385 KSYRLISLLNLHKKRHSGEARYRCGDCGKLFTTSGNLKRH-QLVHSGQKPYQCDYCGRSFSDPTS 448

  Fly   246 R-------DALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGG---------------- 287
            :       |..|:..|..|...|||..|||.|||. |..:..:..||.|
Mouse   449 KMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKI-HIADGPLKCRECGKQFTTSGNLKRHLRIH 512

  Fly   288 AGER-HFCDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDK-L 350
            :||: :.|..||::|.....|:.| ::.|  ..|.|.:|.:||:...:...|:.|:..|:.:| .
Mouse   513 SGEKPYVCTHCQRQFADPGALQRH-VRIH--TGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPY 574

  Fly   351 PCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQA 415
            .||.||:||.:..:|..|:|. |..::|..|..|.::|.:...|..|..||||||||:||.||:.
Mouse   575 VCERCGKRFVQSSQLANHIRH-HDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRG 638

  Fly   416 FRQQTCLKNHRK-VHE 430
            |.:...|::|.| ||:
Mouse   639 FNRVDNLRSHVKTVHQ 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	10/44 (23%)
		C2H2 Zn finger	158..179	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..209	CDD:275368	6/20 (30%)
		C2H2 Zn finger	218..239	CDD:275368	5/46 (11%)
		C2H2 Zn finger	254..275	CDD:275368	11/20 (55%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	325..345	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	9/20 (45%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	8/20 (40%)
Zbtb17	NP_001365755.1	BTB_POZ_ZBTB17_MIZ1	2..113	CDD:349515
		PRK07003	<115..>266	CDD:235906	16/69 (23%)
		COG5048	322..653	CDD:227381	97/342 (28%)
		C2H2 Zn finger	324..344	CDD:275368	7/20 (35%)
		C2H2 Zn finger	352..372	CDD:275368	6/20 (30%)
		C2H2 Zn finger	380..400	CDD:275368	2/19 (11%)
		C2H2 Zn finger	408..428	CDD:275368	4/20 (20%)
		C2H2 Zn finger	436..456	CDD:275368	1/19 (5%)
		C2H2 Zn finger	464..484	CDD:275368	11/20 (55%)
		C2H2 Zn finger	492..512	CDD:275368	3/19 (16%)
		C2H2 Zn finger	520..540	CDD:275368	6/20 (30%)
		C2H2 Zn finger	548..568	CDD:275368	5/19 (26%)
		C2H2 Zn finger	576..596	CDD:275368	9/20 (45%)
		C2H2 Zn finger	604..624	CDD:275368	5/19 (26%)
		C2H2 Zn finger	632..651	CDD:275370	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100