DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and Zfp160

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_663458.2	Gene:	Zfp160 / 224585	MGIID:	108187	Length:	650	Species:	Mus musculus

Alignment Length:	435	Identity:	116/435 - (26%)
Similarity:	179/435 - (41%)	Gaps:	95/435 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 CLECRSAVQNFEKFRR----------------KADECRKQLLE--MLKKDPR----EPTFEVVYD 110
            ||||..|.     |||                |.:||.|...:  .||...|    |..|:..:.
Mouse   176 CLECGKAF-----FRRSYLLVHERHHTGAKPYKCNECGKVFSQNSHLKSHRRIHTGEKPFKCNHC 235

  Fly   111 GREEDQES-------LHGLEPPEPAPDPDPI----------------DEP----------AIKSD 142
            |:.....|       :|..:.|....:...:                ::|          :..|:
Mouse   236 GKAFSVRSNLTHHQVIHTGDKPYKCNECGKVFSQTSSLTIHRRTHTGEKPYRCNECGKVFSSHSN 300

  Fly   143 KSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIRE 207
            .:..::........|||.|.:.|.....||.|.| :|.|.| |::|::|.||:|....|.|| :.
Mouse   301 LNTHQAIHTGEKPYKCSECGKVFTQNSHLANHWR-IHTGEK-PYKCNECGKAFSVYSSLTTH-QA 362

  Fly   208 VHAPKERRHPCDQPGCERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYHLK 272
            :|. .|:.:.|::  |.:::|....:..|:.: ||..     |.:.||:||..|:|::||..|.:
Mouse   363 IHT-GEKPYKCNE--CGKVFTQNSHLASHRGV-HSGE-----KPYKCEECGKLFSQTSNLARHWR 418

  Fly   273 TKHPTEDEVAAREGG----------------AGERHF-CDICQKEFHSRYTLKYHTLQQHEVQEE 320
            . |..|......|.|                .||:.: |..|.|.|....:|..|   |.....|
Mouse   419 V-HTGEKPYKCSECGKAFSVRSSLIAHQVIHTGEKPYKCTECGKVFSQTSSLSIH---QRIHTGE 479

  Fly   321 LPHECQVCGRRMAKKFMLLQHMLMHSNDK-LPCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHC 384
            .|:.|..||:.......|..|.::|:..| ..|..||:.|.:...|..|.| .|...||:.|:.|
Mouse   480 KPYRCNECGKAFNSHSNLNTHQVIHTGQKPYKCMQCGKVFTQNSHLANHQR-THTGEKPYKCNEC 543

  Fly   385 PESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCLKNHRKVH 429
            .::|:...:|..|:.||||||||.|:.||:.|.|.:.|.:||:.|
Mouse   544 GKAFSVYSSLTTHQAIHTGEKPYKCNECGKVFTQNSHLASHRRTH 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	12/44 (27%)
		C2H2 Zn finger	158..179	CDD:275368	8/20 (40%)
		C2H2 Zn finger	188..209	CDD:275368	8/20 (40%)
		C2H2 Zn finger	218..239	CDD:275368	4/20 (20%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	325..345	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	8/19 (42%)
Zfp160	NP_663458.2	KRAB	8..68	CDD:214630
		KRAB	8..47	CDD:279668
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368	8/24 (33%)
		zf-H2C2_2	188..213	CDD:290200	4/24 (17%)
		COG5048	200..635	CDD:227381	108/406 (27%)
		zf-C2H2	202..224	CDD:278523	7/21 (33%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		zf-H2C2_2	216..240	CDD:290200	6/23 (26%)
		C2H2 Zn finger	232..252	CDD:275368	2/19 (11%)
		zf-H2C2_2	244..269	CDD:290200	2/24 (8%)
		C2H2 Zn finger	260..280	CDD:275368	0/19 (0%)
		zf-H2C2_2	272..297	CDD:290200	1/24 (4%)
		C2H2 Zn finger	288..308	CDD:275368	1/19 (5%)
		zf-H2C2_2	300..325	CDD:290200	5/24 (21%)
		C2H2 Zn finger	316..336	CDD:275368	8/20 (40%)
		C2H2 Zn finger	344..364	CDD:275368	8/20 (40%)
		zf-H2C2_2	356..381	CDD:290200	7/28 (25%)
		C2H2 Zn finger	372..392	CDD:275368	4/22 (18%)
		zf-H2C2_2	384..409	CDD:290200	9/30 (30%)
		C2H2 Zn finger	400..420	CDD:275368	9/20 (45%)
		zf-H2C2_2	412..436	CDD:290200	7/24 (29%)
		C2H2 Zn finger	428..448	CDD:275368	2/19 (11%)
		zf-H2C2_2	440..465	CDD:290200	6/24 (25%)
		C2H2 Zn finger	456..476	CDD:275368	7/22 (32%)
		zf-H2C2_2	468..493	CDD:290200	8/27 (30%)
		C2H2 Zn finger	484..504	CDD:275368	5/19 (26%)
		zf-H2C2_2	496..521	CDD:290200	8/24 (33%)
		C2H2 Zn finger	512..532	CDD:275368	7/20 (35%)
		zf-H2C2_2	524..548	CDD:290200	8/24 (33%)
		C2H2 Zn finger	540..560	CDD:275368	5/19 (26%)
		zf-H2C2_2	552..577	CDD:290200	14/24 (58%)
		C2H2 Zn finger	568..588	CDD:275368	8/19 (42%)
		zf-H2C2_2	580..604	CDD:290200	4/9 (44%)
		C2H2 Zn finger	596..616	CDD:275368
		zf-H2C2_2	608..633	CDD:290200
		C2H2 Zn finger	624..644	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930