DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and znf1042

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_021331115.1	Gene:	znf1042 / 103910494	ZFINID:	ZDB-GENE-120703-14	Length:	726	Species:	Danio rerio

Alignment Length:	422	Identity:	115/422 - (27%)
Similarity:	183/422 - (43%)	Gaps:	95/422 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 EKFRRKADECRKQL-LEMLKKDPREPTFEVVYDGREEDQESLHGLEPPEPAPDPDPIDEPAIKSD 142
            |.|..|.::.::|. |.:||::..         |:.|..|.....:|.|...|..|.......|.
Zfish    15 ETFTVKQEDLQEQTDLMVLKEETH---------GQNEIDEKQQFQKPQEIMTDEKPTLTKKTSSH 70

  Fly   143 KSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIRE 207
            ...|||..|.  ...|..||:||:.:..|..|:| ||. .::|:.|:||.|::..:.|...|:|
Zfish    71 GRLRKSKSGC--NFSCKQCRKSFSQKSKLDVHMR-VHT-REQPYTCEQCGKSFGQIQGFKAHMR- 130

  Fly   208 VH---------------------APKERRHPCDQP----GCERIYTSRIAMQKHKRLKHSPRDRD 247
            :|                     |...|.|..::|    .|.:.::.:..:..|.|: |:..
Zfish   131 IHTGEGKFTCQECGKSFYQAGNFAAHMRIHTGEKPFSCKQCGKSFSQKSNLDVHMRV-HTRE--- 191

  Fly   248 ALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGG----------------AGERHF-CD 295
              :.:.|||||.||.|..:.|.|::. |..|.:...:|.|                .||:.| |.
Zfish   192 --QPYTCEQCGKSFGQIQSFKAHMRI-HTGEGKFTCQECGKSFYQAGNFAAHMRIHTGEKPFSCK 253

  Fly   296 ICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDK-LPCEHCGRRF 359
            .|.|.|..:..|..| ::.|  ..|.|:.|:.||:..::|.....||.:|:.:| ..|:.||:.|
Zfish   254 QCGKSFSQKSNLDVH-MRVH--TREQPYTCEQCGKSFSQKQSFNTHMRIHTGEKPFSCKQCGKSF 315

  Fly   360 ARRFELEAHVRA-----------------------VHLKL----KPFPCHHCPESFASRKTLRHH 397
            .::..|:.|:|.                       :|:::    ||:.|..|.:||....||:||
Zfish   316 FQKPNLDVHMRVHTGEKPHTCEQCGKSFGQKQDLYIHMRIHTGEKPYTCTECGKSFPHISTLKHH 380

  Fly   398 EYIHTGEKPYICDTCGQAFRQQTCLKNHRKVH 429
            ..|||||||:.|..||::|..:|.||||..:|
Zfish   381 MRIHTGEKPFACAQCGKSFTTKTSLKNHMMIH 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	5/16 (31%)
		C2H2 Zn finger	158..179	CDD:275368	8/20 (40%)
		C2H2 Zn finger	188..209	CDD:275368	7/20 (35%)
		C2H2 Zn finger	218..239	CDD:275368	3/24 (13%)
		C2H2 Zn finger	254..275	CDD:275368	10/20 (50%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	7/43 (16%)
		C2H2 Zn finger	381..401	CDD:275368	8/19 (42%)
		C2H2 Zn finger	409..429	CDD:275368	9/19 (47%)
znf1042	XP_021331115.1	C2H2 Zn finger	84..104	CDD:275368	8/20 (40%)
		C2H2 Zn finger	112..132	CDD:275368	7/20 (35%)
		C2H2 Zn finger	140..160	CDD:275368	2/19 (11%)
		zf-H2C2_2	152..177	CDD:316026	5/24 (21%)
		C2H2 Zn finger	168..188	CDD:275368	3/20 (15%)
		C2H2 Zn finger	196..216	CDD:275368	10/20 (50%)
		C2H2 Zn finger	224..244	CDD:275368	2/19 (11%)
		zf-H2C2_2	236..261	CDD:316026	7/24 (29%)
		C2H2 Zn finger	252..272	CDD:275368	6/20 (30%)
		COG5048	277..716	CDD:227381	44/136 (32%)
		C2H2 Zn finger	280..300	CDD:275368	6/19 (32%)
		C2H2 Zn finger	308..328	CDD:275368	7/19 (37%)
		C2H2 Zn finger	336..356	CDD:275368	1/19 (5%)
		C2H2 Zn finger	364..384	CDD:275368	8/19 (42%)
		C2H2 Zn finger	392..412	CDD:275368	9/19 (47%)
		C2H2 Zn finger	420..440	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	504..524	CDD:275368
		C2H2 Zn finger	532..552	CDD:275368
		C2H2 Zn finger	560..580	CDD:275368
		C2H2 Zn finger	588..608	CDD:275368
		C2H2 Zn finger	616..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	672..692	CDD:275368
		C2H2 Zn finger	700..718	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910