DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3032 and si:ch211-110e21.4

DIOPT Version :9

Sequence 1:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_009298135.1	Gene:	si:ch211-110e21.4 / 103910350	ZFINID:	ZDB-GENE-131126-43	Length:	241	Species:	Danio rerio

Alignment Length:	293	Identity:	92/293 - (31%)
Similarity:	122/293 - (41%)	Gaps:	59/293 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 IKSDKSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYT 203
            ::|.....|..|.......|:.|.:||.....|..|: ..|.| :|||.|.||.|.::....|..
Zfish     1 MQSSHKIHKMVRTGEKLFTCTQCGKSFTRSSHLNQHM-MTHTG-ERPFTCTQCGKRFTQSSSLNQ 63

  Fly   204 HIREVHAPKERRHPCDQPGCERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLK 268
            ||                   :|:|..                   |.|.|.|||.||..|:.|.
Zfish    64 HI-------------------KIHTGE-------------------KPFKCTQCGKSFTISSLLN 90

  Fly   269 YHLKTKHPTEDEVAAREGGAGER-HFCDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRM 332
            .|:.|.             .||| |.||.|.|.|.:...||.| |:.|..  |.|:.|.|||:..
Zfish    91 RHMLTH-------------TGERKHRCDQCGKTFTTGSFLKLH-LRVHTT--EKPYSCSVCGKGF 139

  Fly   333 AKKFMLLQHMLMHSNDKLP-CEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRH 396
            ..:..|.:|..:|:..|.. |..|.:.|....:||.|.| .|...||:.|.||.:.|:...:||.
Zfish   140 TWRTNLNRHQKIHTGVKEHYCFECWKTFMTADDLERHQR-THTGEKPYTCSHCDKRFSQLGSLRA 203

  Fly   397 HEYIHTGEKPYICDTCGQAFRQQTCLKNHRKVH 429
            ||..|||||||:|..|.:.|.|...|:.|.|:|
Zfish   204 HERTHTGEKPYMCSHCNKRFTQLGALRRHEKIH 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..209	CDD:275368	7/20 (35%)
		C2H2 Zn finger	218..239	CDD:275368	2/20 (10%)
		C2H2 Zn finger	254..275	CDD:275368	10/20 (50%)
		C2H2 Zn finger	294..315	CDD:275368	9/20 (45%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	8/19 (42%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
si:ch211-110e21.4	XP_009298135.1	COG5048	<16..176	CDD:227381	61/215 (28%)
		C2H2 Zn finger	20..40	CDD:275368	6/20 (30%)
		C2H2 Zn finger	48..68	CDD:275368	7/38 (18%)
		C2H2 Zn finger	76..96	CDD:275368	9/19 (47%)
		C2H2 Zn finger	104..124	CDD:275368	9/20 (45%)
		C2H2 Zn finger	132..152	CDD:275368	6/19 (32%)
		C2H2 Zn finger	160..180	CDD:275368	7/20 (35%)
		SFP1	<169..234	CDD:227516	28/65 (43%)
		C2H2 Zn finger	188..208	CDD:275368	8/19 (42%)
		C2H2 Zn finger	216..236	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12262
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000