Protein Alignment cm and APM2

DIOPT Version :10

• Sequence 1: NP_788873.1
• Gene: cm / 31647
• FlyBaseID: FBgn0000330
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_011844.1
• Gene: APM2 / 856367
• SGDID: S000001011
• Length: 605
• Species: Saccharomyces cerevisiae
• Alignment Length: 608
• Identity: 124/608 - (20%)
• Similarity: 213/608 - (35%)
• Gaps: 215/608 - (35%)

  Fly     1 MIHSLFIVNSGGEVFLEKHWRSVVSRSVCEYFLDAQRAAPYD-VPPVIATPHYYLITVQRDTVSL 64
            |..||||::...|..:.|:.|::.:.|   ..|.:.:...:| .||:::...::.|.::||.:..
Yeast     1 MSSSLFILDENLEPLVSKNIRALPNLS---SVLSSFKQCYHDGSPPILSQNDWFFIHLKRDFLHF 62

  Fly    65 VAAC----KQEVPPLFVIEFLHRVVDTFQDYF--GDCSESVIKDNYVVVYELLDEMLDNGFPLAT 123
            |:..    |..:..:.::.||.:.....|.||  ...:::||.||.::|.||:||.:|.|....|
Yeast    63 VSVIHTTDKPNIDLMTILAFLEQFYHLLQKYFEIEVLTKNVILDNILLVLELIDECIDFGIVQVT 127

  Fly   124 ESNILKELIKPP----------------------------------------------------- 135
            :.:|:|:.|:..
Yeast   128 DPSIIKDYIRVKVNVPRVTVDNEEWSPGEESSSSSGSDSDSEYSNTNKRKDKKKKRKKKKGTKGK 192

  Fly   136 --------------------NILRTIANTV-----TGKSNVSTTLP--------SGQLS-----A 162
                                |::.|:..|:     |||...:..||        :|.::     .
Yeast   193 SVGKSKLKSIMVNNKENRGINVVETVKETLRNKNDTGKEAANDELPNDGNDLYINGDIAKTIIMP 257

  Fly   163 VRWRRSGVRYTNNEAYFDVIEEVDAIIDKSGSTVFAE-IQGHIDCCIKLSGMPDLTLSF-----M 221
            :.||..|:.|..||.:.||||.|..::|.....:... |.|.|.|...|||||.|.:|.     .
Yeast   258 ISWRTKGIHYAKNEFFLDVIERVQYLMDFEKGVIRKNLIHGEIVCRCYLSGMPKLKISINKILNR 322

  Fly   222 NPRLFDDVSFHPCV-----------RYKRWEAE---------RLLSFIPPDGNFRLMSY----HI 262
            :|:...:.|||.||           ..|..:.:         |.:.||||||.|.|..|    |:
Yeast   323 DPQFMSNSSFHQCVSLDSINTIEKDEEKNSDDDAGLQAATDAREIEFIPPDGEFVLCQYELKRHV 387

  Fly   263 SSQSVVAIPIY----------------IRHNFSIKTGEQGRLDLTIGPRNTLGRTVDKVKLELTM 311
            ....:|.:..:                |:.||. .|....:|::.|    .|.:...:.|::|:.
Yeast   388 KDAPMVRLKDFEIKPKLKKFKIQIVTKIQTNFK-PTNSTSKLNVRI----PLTKVFQEYKIDLSK 447

  Fly   312 PRCVLNCLLTPNQGKYTFDSVTKTLSWDVGRID--------------------------VSKLP- 349
                 ......|.||..|:.....|.|::..:.                          |::.|
Yeast   448 -----QIRFKANIGKVVFNLSDDFLLWEIQTMKGHREHSTNKSSQYNSDEDDPNTCASMVAEFPL 507

  Fly   350 -----------NIRGSVSITP-----------------GTTNIDANPS-VNVQFQISQLAVSGLK 385
                       .::.|::..|                 .|:::..... ||:.|:|.....||||
Yeast   508 FNQEEYDRLQEEMKTSMNPPPLRTGPRLEELYRQVHDQQTSHVTPRDKLVNIDFEIPYCTCSGLK 572

  Fly   386 VNRLDMYGE--KYKPFKGVKYLT 406
            |..|.:...  :|:.|..|:|.|
Yeast   573 VEYLKVEEPQLQYQSFPWVRYKT 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cm	NP_788873.1	AP3_Mu_N	3..139	CDD:341441	38/215 (18%)
		AP_MHD_Cterm	163..414	CDD:472082	77/348 (22%)
APM2	NP_011844.1	AP_Mu_N	3..138	CDD:341432	37/137 (27%)
		AP-1_Mu1_Cterm	256..603	CDD:271158	77/350 (22%)