DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cm and stnB

DIOPT Version :9

Sequence 1:	NP_001259302.1	Gene:	cm / 31647	FlyBaseID:	FBgn0000330	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001036318.2	Gene:	stnB / 4379834	FlyBaseID:	FBgn0016975	Length:	1262	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	99/537 - (18%)
Similarity:	173/537 - (32%)	Gaps:	181/537 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LFIVNSGGEVFL----------EKHWRSVVSR-------SVCEYFLDAQRAAPYDVPPVIATPHY 52
            |..:..|.|:.|          ::.|:.:|.|       .|.:....|....|:...|:  .|.|
  Fly   722 LHYIGPGWEMQLRQPNKKKITGQRFWKKIVVRLVVQNDVPVVQLLNQAGDKQPFQELPL--QPSY 784

  Fly    53 YLITV---QRDTVSLVAACKQE---------VPPLFVIEFLHRVVDTFQDYFGDCSESVIKDNYV 105
            .:..:   |.|....:...|.:         |.|..|.: ..|:.:....:    ::..|..:|.
  Fly   785 SVSEIGAQQYDQFGKIFTMKLQYIFYKERPGVRPGQVTK-AERITNKLTKF----AQYAIAGDYE 844

  Fly   106 VVYELLDEMLDNGFPL--ATESNILKELIKPPNILRTIANTVTGKSN------VSTTLPSGQLSA 162
            .|.|...::...|.|:  |.:|:.|.::               |..|      .|..:.......
  Fly   845 GVKEFGSDLKKLGLPVEHAPQSSQLFKI---------------GSMNYEDMKQFSVCIEEALFKI 894

  Fly   163 VRWRRSGVRYTNNEAYFDVIEEVDAIIDKSGSTVFAEIQGHIDCCIK------------LSGMPD 215
            ...|...:.|...|.....::|:         ||..:.:|.|   :|            |:|||.
  Fly   895 PALRERALTYKMEEVQVTAVDEI---------TVEQDFEGKI---LKQIARVRLFFLAFLTGMPT 947

  Fly   216 LTLSFMNP----------------------RLFDDVSFHPCVRYKRWEAERLLSFIPPDGNF-RL 257
            :.|...:.                      || :.|.||..|..|.:|..|.:.|.|||.|: .|
  Fly   948 IELGVNDMWRQGKEVVGRHDIIPVATEEWIRL-EAVEFHSVVNQKEYERTRTIKFQPPDANYIEL 1011

  Fly   258 MSYHISSQSVVAIPIYIRHNFSIKTGE-QGRLDLTIGPRNT---LGR-TVDKVKLELTMPRC--- 314
            :.:.:.......:|:.::..:.:...: :.|.|:.: |..|   ||: ..:.|.:...:|.|
  Fly  1012 LRFRVRPPKNRELPLQLKATWCVSGNKVELRADILV-PGFTSRKLGQIPCEDVSVRFPIPECWIY 1075

  Fly   315 ----------------------------VLNCL---------LTPNQGKYTFDSVTKTLSWDVGR 342
                                        :|..:         :|..|.||  :...:.:.|...|
  Fly  1076 LFRVEKHFRYGSVKSAHRRTGKIKGIERILGAVDTLQESLIEVTSGQAKY--EHHHRAIVWRCPR 1138

  Fly   343 IDVSKLPNIRGSVSITP-------GTTNIDANPS-----VNVQF-----QISQLAVSGLKVNRLD 390
                 ||. .|..:.|.       ..|:.|..||     ..|:|     |:|...|..:.|.  |
  Fly  1139 -----LPK-EGQGAYTTHQLVCRMALTSYDQIPSELAPYAFVEFTMPATQVSHTTVRSVSVQ--D 1195

  Fly   391 MYGEKYKPFKGVKYLTK 407
            ..|:: .|.|.|:||.:
  Fly  1196 SDGDE-PPEKYVRYLAR 1211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cm	NP_001259302.1	AP_MHD_Cterm	163..414	CDD:299401	67/342 (20%)
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603
stnB	NP_001036318.2	AP_MHD_Cterm	897..1219	CDD:299401	67/340 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439811
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940