DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Inx2 and inx-21

DIOPT Version :9

Sequence 1:	NP_001162684.1	Gene:	Inx2 / 31646	FlyBaseID:	FBgn0027108	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_491187.2	Gene:	inx-21 / 171930	WormBaseID:	WBGene00002143	Length:	481	Species:	Caenorhabditis elegans

Alignment Length:	412	Identity:	80/412 - (19%)
Similarity:	149/412 - (36%)	Gaps:	91/412 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVFGSVKGLLKIDQVCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDC-IVDEIPLGVMDT 66
            |....::||        ::...::.:..|:.||:...:|:.|:...|.||.| :..:.|...:|.
Worm    11 DPLKRIRGL--------ESGTEKLLHNTTIAILVFLFILLASKPMFGSPIVCQVPKDWPSSSVDY 67

  Fly    67 Y---CWI--YSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVP 126
            :   |:.  .....:..|::...||..|...:   ..|..|     :|.||..|......|..:|
Worm    68 FTDICYYGQREKVDIQHRISRAGGRGTVTVNL---TTGTSE-----FYMWVPLVPILLVALCLLP 124

  Fly   127 RYLWK------------------------------SWEGGRLKMLVMDLNSPIV---NDECKNDR 158
            .:.||                              ..||.|.:.|...||..|:   |..|...:
Worm   125 AFFWKFVGLDCFNGMDIVSFLEFYEQTDDPGERLVEMEGWRRRKLAAQLNKWIMAKRNFFCGLSQ 189

  Fly   159 KKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDE 223
            ..|:  |.:....|...:..:|::              ..|.|.||.|....:|:.:...   .:
Worm   190 TMII--YVLMKWFRTILFIAQFWI--------------IADVFGDGNFFWGYADLARIAN---GD 235

  Fly   224 RIDPMARVFPKVTKCTFHKYGPS-----GSVQTHDGL--CVLPLNIVNEKIYVFLWFWFIILSIM 281
            .|:|:...|..::.|...:...|     .....|..:  |:|..|.:|.|.::.|::||:::|.:
Worm   236 SINPLKGSFTLISGCRVQRLAMSIGFYRSYTNAHSAVARCMLSANFLNAKAFLVLYWWFLLVSFI 300

  Fly   282 SGISLIYRIAVVAGPKLRHLLLRARSRLAESEEVELVAN---KCNIGD----WFLLYQLGKNIDP 339
            |..|.|:...::..|:.|....::..| .|...:|....   ..::|.    .:|:..||.  |.
Worm   301 SLCSAIHYTIILLVPQYRRHEFKSMIR-TEDHFIERYGEPHPNLHLGKEAPLEYLVEHLGN--DG 362

  Fly   340 LIYKEVISDLSREMSGDEHSAH 361
            .:..|::.|:......|..:.|
Worm   363 FLVVEMVYDMLHHYECDRFTEH 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inx2	NP_001162684.1	Innexin	1..351	CDD:295599	78/400 (20%)
inx-21	NP_491187.2	Innexin	20..389	CDD:279248	77/395 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010