DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4586 and acad9

DIOPT Version :9

Sequence 1:	NP_572371.1	Gene:	CG4586 / 31641	FlyBaseID:	FBgn0029924	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001038772.1	Gene:	acad9 / 724002	ZFINID:	ZDB-GENE-060616-196	Length:	630	Species:	Danio rerio

Alignment Length:	592	Identity:	117/592 - (19%)
Similarity:	201/592 - (33%)	Gaps:	165/592 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LSGSLGTGLFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNR---SWHMDGVLGTYAQTELGHGT 163
            |.||:       :..|..|.::.:..:|..||:.|:|::|.:   ..|    :..:..||.|.|:
Zfish   144 LDGSI-------AVTLAAHQAIGLKGILIAGTDAQKAKYLPKLATGEH----IAAFCLTEPGSGS 197

  Fly   164 FVRGLETRADYDPITQEFILNTPTQSSYKWWPGGLGNTANVAIVLAQLYV-------KGKHYGLQ 221
            ....::.||......:.::||     ..|:|... |..|::..|.|:..|       |.|   :.
Zfish   198 DAASIQLRATLTEDGKHYLLN-----GTKFWISN-GGWADIMTVFARTEVVDKDGQKKDK---IT 253

  Fly   222 SFVVRIRDERTHEPLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQML------MKNA-QVLT 279
            :|:|    ||.   ..||..|....:||..|.|...:...|.::|...::      .|.| .:|.
Zfish   254 AFIV----ERA---FGGVTSGKPEDKLGIRGSNTTEITFEDTKVPIENVIGEVGDGFKVAMNILN 311

  Fly   280 DGTFVQGRPPLLLYGTMVYVRVITVKDVLFGLLQAATIATRYSVVRRQSRINSDQPEVSVLDHIT 344
            :|.|..|..     |..|..::|.        |.|....||....||.|.....|.:.:.:....
Zfish   312 NGRFSMGGA-----GAGVVKKLIE--------LSAEYAGTRKQFNRRLSEFGMIQDKFATMALNV 363

  Fly   345 QQAKILPQIARGVSYRLVSDWLWRFYEDVLRQLEDESTKGRNSLPELHALSCCLKAVATDE---- 405
            ...:.:..:..|:                         ..|..||:....:..:|..:::.
Zfish   364 YVMESMAYLTAGM-------------------------MDRPGLPDCSLEAAMVKVFSSEGTWIC 403

  Fly   406 ASEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQYADSLKRKVLP 470
            .||.:.:|    ||.||..:..::...........:||...:|.:..| ....|:|.    |:|.
Zfish   404 VSEALQVL----GGLGFTKNYPYERYLRDCRILQIFEGTNEILRMYVA-LTGMQHAG----KILT 459

  Fly   471 SSVSYLRDTARLIWGKNLVANCVRALEISAMEQVRDAWQTQKMHQSGK---VSPEMASNLAGRQL 532
            ..:..::.           .|.....||.. ::::|..||.....:||   |.|         .|
Zfish   460 GKIKEMKK-----------GNLGVVFEILG-KKIKDTVQTADFGLTGKDGVVHP---------SL 503

  Fly   533 TSAAIAHAHAFFTRNALEQVEALRKKGDLSPNVSLILGQLVELFVIDTFLRQSGCVLRWNNGITG 597
            |.:|     ..|.:||                  ...|..||           |.:.|:...|..
Zfish   504 TESA-----KMFEQNA------------------ACFGSTVE-----------GLLYRYGKTIVD 534

  Fly   598 TQLRFVERRFEELL-------AKLRPNAVALVDGFDFHD-RVLGSTLGCHDGRVYERLM--EEAR 652
            .||  :.::..::|       |.|..::.::..|...|| .||.:...|.|.......|  :..|
Zfish   535 EQL--LLKKVADVLINLYAMTAVLSRSSRSISIGLRNHDHEVLLTNTFCKDAHFKNNYMLSQLQR 597

  Fly   653 RNPINQE 659
            .:|.|.:
Zfish   598 YSPENDD 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:299127	114/584 (20%)
CG4586	NP_572371.1	PLN02443	7..677	CDD:178062	117/592 (20%)
acad9	NP_001038772.1	CaiA	75..447	CDD:224871	74/371 (20%)
acad9	NP_001038772.1	VLCAD	48..455	CDD:173850	76/380 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810