DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4586 and Acads

DIOPT Version :9

Sequence 1:	NP_572371.1	Gene:	CG4586 / 31641	FlyBaseID:	FBgn0029924	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_071957.1	Gene:	Acads / 64304	RGDID:	620514	Length:	414	Species:	Rattus norvegicus

Alignment Length:	488	Identity:	105/488 - (21%)
Similarity:	184/488 - (37%)	Gaps:	118/488 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 AAATLDSEDFARWWAGGS-GQLEERRALERRFY----------EDPDFAEPVHPSCLSYKERYEQ 65
            |||.|     ||  |||| |     |||..|.:          |.|:..:.:..:|..:.|:...
  Rat     4 AAALL-----AR--AGGSLG-----RALRARDWRRLHTVYQSVELPETHQMLRQTCRDFAEKELV 56

  Fly    66 TVARSTRFLAKLRQWQREKQPQLQLS-VNMLRDFRLL-------LSGS-------------LGTG 109
            .:|.           |.:|:.....| |..:.:..||       |||:             :..|
  Rat    57 PIAA-----------QLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRG 110

  Fly   110 LFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLETRADY 174
            .......:.|:.|:::..:|..|:.:|:.||:....:.|.: |.:|.:|.|:|:......|.|..
  Rat   111 CASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKI-GCFALSEPGNGSDAGAASTTARE 174

  Fly   175 DPITQEFILN-TPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTG 238
            :  ...::|| |....:..|       .|:..:|.|......::.|:.:|:|.:       |..|
  Rat   175 E--GDSWVLNGTKAWITNSW-------EASATVVFASTDRSRQNKGISAFLVPM-------PTPG 223

  Fly   239 VDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQMLMKNAQVLTDGTFVQGRPPLLLYGTMVYVRV-- 301
            :.:|....:||....:...|...|.|||:..:|              |.|.:   |..:.::.
  Rat   224 LTLGKKEDKLGIRASSTANLIFEDCRIPKENLL--------------GEPGM---GFKIAMQTLD 271

  Fly   302 ---ITVKDVLFGLLQAA-TIATRYSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRLV 362
               |.:.....|:.||: ..|.:|:    ::|.....| ::.|.:|  |.|:........|.||:
  Rat   272 MGRIGIASQALGIAQASLDCAVKYA----ENRHAFGAP-LTKLQNI--QFKLADMALALESARLL 329

  Fly   363 SDWLWRFYEDVLRQLEDESTKGRNSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSAN 427
            : |.....:|..:....||...:.:..|          .||..:.:.:.:|    ||.|:::...
  Rat   330 T-WRAAMLKDNKKPFTKESAMAKLAASE----------AATAISHQAIQIL----GGMGYVTEMP 379

  Fly   428 FDSIYGLTAATYTYEGEYTVLLLQTARFLVRQY 460
            .:..|.....|..|||...:..|..|..|:|.|
  Rat   380 AERYYRDARITEIYEGTSEIQRLVIAGHLLRSY 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:299127	105/488 (22%)
CG4586	NP_572371.1	PLN02443	7..677	CDD:178062	105/488 (22%)
Acads	NP_071957.1	CaiA	35..414	CDD:224871	90/445 (20%)
Acads	NP_071957.1	SCAD_SBCAD	38..410	CDD:173847	86/438 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810