DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4586 and acadvl

DIOPT Version :9

Sequence 1:	NP_572371.1	Gene:	CG4586 / 31641	FlyBaseID:	FBgn0029924	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_997776.1	Gene:	acadvl / 573723	ZFINID:	ZDB-GENE-030131-899	Length:	659	Species:	Danio rerio

Alignment Length:	578	Identity:	116/578 - (20%)
Similarity:	202/578 - (34%)	Gaps:	161/578 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LGTGLFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLET 170
            ||.|:     .|..|.|:....:|..|..:|:.::|.:....:.: ..:..||...|:....::|
Zfish   177 LGVGI-----TLGAHQSIGFKGILLFGNPQQKEKYLPKLATGENI-AAFCLTEPASGSDAASIKT 235

  Fly   171 RADYDPITQEFILNTPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYG-----LQSFVVRIRDE 230
            .|...|..|.:.:|     ..|.|... |.||.:..|.|:..||.:..|     :.:|:|    |
Zfish   236 TAVRSPCGQYYTMN-----GSKIWISN-GGTAEIFTVFAKTPVKDEKTGEMKDKITAFIV----E 290

  Fly   231 RTHEPLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQML------MKNA-QVLTDGTFVQGRP 288
            |:   ..||..|....::|....|...:...:||:|.:.:|      .|.| .:|.:|.|...
Zfish   291 RS---FGGVSSGPPEKKMGIKASNTAEVYFENVRVPADCVLGEVGGGFKVAMNILNNGRFGMA-- 350

  Fly   289 PLLLYGTMVYVRVITVKDVLFGLLQAATIATRY-SVVRRQSRINSDQPEVSVLDHITQQAKILP- 351
             ..|.|||        |.|:...:..|...|:: :.:.....|......:::|.::|:....:.
Zfish   351 -AALSGTM--------KGVITKAVDHAANRTQFGNKIHNYGAIQEKMARMAMLQYVTESMAYMVS 406

  Fly   352 ----------QIARGVSYRLVSDWLWRFYEDVLRQLEDESTKGRNSLPELHALSCCLKAVATDEA 406
                      ||...:|....|:..|                                 :.|||.
Zfish   407 GNMDSGATEFQIEAAISKIFASEAAW---------------------------------LVTDEC 438

  Fly   407 SEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQYADSLK--RKVL 469
            .:.:       ||.||:..|..:.:.........:||...:|.|..|....:...:.||  :|.|
Zfish   439 IQVM-------GGMGFMKDAGVERVLRDLRIFRIFEGTNDILRLFVALNGFQNAGNQLKSLQKAL 496

  Fly   470 PSSVSYLRDTARLIWGKNLVANC-VRALEISAMEQVRDAWQTQKMHQSGKVSPEMASNLAGRQLT 533
                            ||.:.|. :.|.||:...: |.|.....:...|.|.||:  |.:| :||
Zfish   497 ----------------KNPLGNAGMLAGEITKRAK-RRAGLGSGLTLQGTVHPEL--NHSG-ELT 541

  Fly   534 SAAIAHAHAFFTRNALEQVEALRKKGDLSPNVSLILGQL----VELFVIDTFLRQSGCVLRWNNG 594
            ..||....|...       |.|.|.|....:...:|.::    ::|:.:...|.::...|  |.|
Zfish   542 VKAIEQFGAVIE-------ELLLKHGKKIIDEQFVLKRVADCAIDLYAMVVVLSRASRSL--NQG 597

  Fly   595 ITGTQLRFVERRFEELLAKLRPNAVALVDGFDFHDRVLGSTLGCHDGRVYERLMEEAR 652
            .:..|                            |:::|..| .|.:  .:||:|::.:
Zfish   598 HSSAQ----------------------------HEKMLCET-WCTE--AHERVMQDIK 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:299127	116/578 (20%)
CG4586	NP_572371.1	PLN02443	7..677	CDD:178062	116/578 (20%)
acadvl	NP_997776.1	VLCAD	77..486	CDD:173850	75/378 (20%)
acadvl	NP_997776.1	CaiA	107..478	CDD:224871	74/370 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910