Protein Alignment CG4586 and ACOXL

DIOPT Version :10

• Sequence 1: NP_572371.1
• Gene: CG4586 / 31641
• FlyBaseID: FBgn0029924
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001424529.1
• Gene: ACOXL / 55289
• HGNCID: 25621
• Length: 610
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 150/568 - (26%)
• Similarity: 237/568 - (41%)
• Gaps: 76/568 - (13%)

  Fly    66 TVARSTRFLAKLRQWQREKQPQLQLSVNMLRDFRLLLSG------SLGTGLFQQSFPLRVHFSMF 124
            ||.| .:|...|...:|..|...:.:.|.:.  |.|:.|      .:.||:     ...:.:.:|
Human     5 TVQR-VKFAMDLPLLKRAGQDLAEKTKNFVS--RSLVIGEVLSMADMATGV-----KCGIIYWLF 61

  Fly   125 MTTLLSQGTEEQQAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLETRADYDPITQEFILNTPTQS 189
            ...:.:.|:.|...:|. :........|.:|.||.|||:..||::|.|.:|...|||:::||.::
Human    62 GGAIRNLGSPEHVTKWF-QPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCEN 125

  Fly   190 SYKWWPGGLGNT--ANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGGNG 252
            :.|.:   :||.  .|.|.|.|||.:.|:..|...|:|.:||| ......||...|:..:.|.:|
Human   126 AEKMY---IGNAMYGNYAAVFAQLIIDGRSQGPHCFIVPVRDE-NGSLYPGVTAIDMMYKEGLHG 186

  Fly   253 VNNGFLGLRDVRIPRNQMLMKNAQVLTDGTFVQGRPPL--------LLYGTMVYVRVITVKDVLF 309
            |:||.|....|||||..:|.|...|..||   |...|:        .:...:...|:......:.
Human   187 VDNGILIFDKVRIPRENLLDKFGSVAPDG---QYHSPIRNKSARFNAMLAALTPSRLAVAFQAMG 248

  Fly   310 GLLQAATIATRYSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRLVSDWLWRFY-EDV 373
            .:....|||.|||..|||....:.: ||.:::|.||..:::|.:|..::...||.:..... |||
Human   249 AMKLGLTIAIRYSHSRRQFGPKTKE-EVKIIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDV 312

  Fly   374 LRQLEDESTKGRNSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSANFDSIYGLTAAT 438
            .:..|..:::      .|.||...|||.:|.|....:...|:..||.|::.......:...|...
Human   313 FQGKELVNSR------SLQALVAGLKAYSTWENIRCLQDCRECTGGMGYMMENRISGLKCDTDVF 371

  Fly   439 YTYEGEYTVLLLQTARFLVRQYADSLKRKVL-------PSSVSYLRDTARLIWGKNLVANCVRAL 496
            .|:||:..|:|....|.|:.||....:.|.|       ..||.....|:.|.:..:.|.:....|
Human   372 ATFEGDDVVMLQVVGRELLAQYTKQYEEKPLFGLLQNWAESVGDKLRTSFLAFNMDTVDDLAFLL 436

  Fly   497 E-ISAMEQVRDAWQTQKMHQSGKVSPE---MASNLAGRQLTSAAIAHAHAFFTRNALEQVEALRK 557
            : :...|:|.......:::...|...|   .|.|.....:.|.::||.|    |..|||.....|
Human   437 KAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLSLAHTH----RVTLEQFSLAVK 497

  Fly   558 KGDLSPNVSLILGQLVELFVIDTFLRQSGCVLRWNNGITGTQLRFVER 605
            .   .|:..            |..|....|:|      .||:|.|.||
Human   498 S---CPDQE------------DQTLLMKFCLL------YGTKLVFQER 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:447864	150/568 (26%)
ACOXL	NP_001424529.1	None