Protein Alignment CG4586 and Acox1

DIOPT Version :10

• Sequence 1: NP_572371.1
• Gene: CG4586 / 31641
• FlyBaseID: FBgn0029924
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_059036.1
• Gene: Acox1 / 50681
• RGDID: 619757
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 684
• Identity: 278/684 - (40%)
• Similarity: 388/684 - (56%)
• Gaps: 41/684 - (5%)

  Fly     3 VNADLQRERAAATLDSEDFARWWAGGSGQLEERRALERRFYEDPDFAEPVHPSCLSYKERYEQTV 67
            :|.||::|||:||.:.|.......|.......||.:|.....||||....: :.|:..:|||..|
  Rat     1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDY-NFLTRSQRYEVAV 64

  Fly    68 ARSTRFLAKLRQWQREKQPQLQLSVNMLRDFRLLLSGSLGTGLFQQSF--PLRVHFSMFMTTLLS 130
            .:|...:.|:|::......::..       |:         .|:..:|  |:.:::|||:.|||:
  Rat    65 KKSATMVKKMREYGISDPEEIMW-------FK---------KLYLANFVEPVGLNYSMFIPTLLN 113

  Fly   131 QGTEEQQAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLETRADYDPITQEFILNTPTQSSYKWWP 195
            |||..||.:|:..|..:. ::|||||||:||||.:|||||.|.|||.|||||||:||.:|.||||
  Rat   114 QGTTAQQEKWMRPSQELQ-IIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWP 177

  Fly   196 GGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGGNGVNNGFLGL 260
            ||||.|:|.|||||||..:|:.|||.:|||.||:..||:||.|:.||||||:.|...::||:|.:
  Rat   178 GGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKM 242

  Fly   261 RDVRIPRNQMLMKNAQVLTDGTFVQGRPPLLLYGTMVYVRVITVKDVLFGLLQAATIATRYSVVR 325
            .:.||||..||||.|||..|||:|:.....|.|||||:||...|.:....|.:|.|||.|||.||
  Rat   243 DNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVR 307

  Fly   326 RQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRLVSDWLWRFYEDVLRQLEDESTKGRNSLPE 390
            |||.|...:||..:||..|||.|:.|.:|...::..|..::...|   ||..|.......:.|||
  Rat   308 RQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETY---LRINESIGQGDLSELPE 369

  Fly   391 LHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARF 455
            ||||:..|||..|..|:.|::..|.:|||||:..|:...:||.......|:|||.||::||||||
  Rat   370 LHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARF 434

  Fly   456 LVRQYADSLKRKVLPSSVSYLRD--TARL------IWGK----NLVANCVRALEISAMEQVRDAW 508
            |::.|......|::...||||.|  :.|:      :|..    |.:.....|.::.|...|..|.
  Rat   435 LMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAA 499

  Fly   509 QTQKMHQSGKVSPEMASNLAGRQLTSAAIAHAHAFFTRNALEQVEALRKKGDLSPNVSLILGQLV 573
            :..:.|.|.:.|.|:|.||....|..|:.||.|....:...:::..::.|.     |..:|..|.
  Rat   500 KNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKA-----VQAVLRNLC 559

  Fly   574 ELFVIDTFLRQSGCVLRWNNGITGTQLRFVERRFEELLAKLRPNAVALVDGFDFHDRVLGSTLGC 638
            .|:.:....::.|..|. .:.|||.||..|..|..|||..:|||||||||.|||.|..|||.||.
  Rat   560 LLYSLYGISQKGGDFLE-GSIITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGR 623

  Fly   639 HDGRVYERLMEEARRNPINQEPVNSSFHNHLLPM 672
            :||.|||.|.|.|:::|:|:..|:.|:|.||.|:
  Rat   624 YDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPL 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:447864	269/660 (41%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	269/661 (41%)
		Microbody targeting signal. /evidence=ECO:0000255	659..661