DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4586 and CG4860

DIOPT Version :9

Sequence 1:	NP_572371.1	Gene:	CG4586 / 31641	FlyBaseID:	FBgn0029924	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	107/508 - (21%)
Similarity:	174/508 - (34%)	Gaps:	161/508 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RAAATLDSEDFARW----WAGGSGQLEERRALERRFYEDPDFAEPVHPSCLSYKERYEQTVARST 71
            |.|.||.......|    .|||:..:                      :||:......|.:.::.
  Fly     6 RVARTLGQRSSGAWSARIIAGGNRGI----------------------ACLAALSETHQILQKTC 48

  Fly    72 RFLA------KLRQWQREK-QPQLQ---------LSVNMLRDFRLLLSGSLGTGLFQQSFPLRVH 120
            |..|      |.|...||: .|..|         :||.:..::.       |:||..|::.:.:.
  Fly    49 REFANAELAPKARHHDREELYPAEQVRRLGELGLMSVTVREEYG-------GSGLDYQAYAIGME 106

  Fly   121 ---------------FSMFMTTLLSQGTEEQQAQWL---NRSWHMDGVLGTYAQTELGHGTFVRG 167
                           .::::..:...|||:|:..:|   .:..|    :..||.:|.|:|:....
  Fly   107 EVARGDAAVSIVMGVNNLYLGAVQQHGTEQQKQDFLVPYTQGEH----IAFYALSEPGNGSDAGA 167

  Fly   168 LETRA----DYDPI--TQEFILNTPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVR 226
            ..|.|    |...|  |:.:|.|:...|      ||        ||.|.:....||.|:.:|:
  Fly   168 ASTTAKLQGDSYQINGTKAWISNSKEAS------GG--------IVFATVDKSMKHKGITAFL-- 216

  Fly   227 IRDERTHEPLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQML------MKNAQVLTDGTFVQ 285
                 |.:.:.|:.:.....::|....:...|.|.||.:||:::|      .|.|....|    .
  Fly   217 -----TPKDVPGLSIAKKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLD----C 272

  Fly   286 GRPPLLLYGTMVYVRVITVKDVLFGLLQAA-TIATRYSVVRRQSRINSDQPEVSVLDHITQ---- 345
            ||..:....|              |:.||| .:|..||           |..|:...|:.:
  Fly   273 GRIGIAAQAT--------------GIAQAALELAVDYS-----------QKRVAFGKHLARLQLI 312

  Fly   346 QAKILPQIARGVSYRLVSDWLWRFYEDVLRQLEDESTKGRNSLPELHALSCCLKAVATDEASEGV 410
            |.|:.....|....||::   ||     ...|:|      |.||....     .|:|...|||..
  Fly   313 QQKLADMATRVEISRLLT---WR-----AAWLKD------NGLPITKE-----AAMAKLHASESA 358

  Fly   411 DLLRKSC----GGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQ 459
            ......|    ||.|:.:....:..|.....|..|||...:..:..|..::|:
  Fly   359 TFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAVLRE 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:299127	107/508 (21%)
CG4586	NP_572371.1	PLN02443	7..677	CDD:178062	107/508 (21%)
CG4860	NP_650163.2	CaiA	37..414	CDD:224871	97/455 (21%)
CG4860	NP_650163.2	SCAD_SBCAD	39..410	CDD:173847	96/450 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460774
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740