DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4586 and Gcdh

DIOPT Version :9

Sequence 1:NP_572371.1 Gene:CG4586 / 31641 FlyBaseID:FBgn0029924 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_001102366.1 Gene:Gcdh / 364975 RGDID:1308829 Length:447 Species:Rattus norvegicus


Alignment Length:476 Identity:102/476 - (21%)
Similarity:165/476 - (34%) Gaps:168/476 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 EQTVARSTRFLAKLRQWQREKQP-----QLQLSVNMLRD-----------FRLLLS--------- 103
            |:|..||.:....:..|   |.|     ||.....::||           .|:||:         
  Rat    43 EKTQIRSVKSSRPVFDW---KDPLVLEEQLTADEKLIRDTFRNYCQERLMSRILLANRNEVFHRD 104

  Fly   104 -----GSLGT------------------GLFQQSFP---------LRVHFSMFMTTLLSQGTEEQ 136
                 |.||.                  ||..:...         :.|..|:.|..:.:.|:|||
  Rat   105 IVYEMGELGVLGPTIKGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYTYGSEEQ 169

  Fly   137 QAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLETRADYDPI--------TQEFILNTPTQSSYKW 193
            :.::|.|....: :||.:..||..||:....:||||.::|.        |:.:|.|:|....:..
  Rat   170 RQKYLPRLAKGE-LLGCFGLTEPNHGSDPGSMETRARHNPSNKSYTLSGTKTWITNSPVADLFVV 233

  Fly   194 WPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGG----NGVN 254
            |.....|     .:...|..||.. ||.:                       ||:.|    ....
  Rat   234 WARCEDN-----CIRGFLLEKGMR-GLSA-----------------------PRIEGKFSLRASA 269

  Fly   255 NGFLGLRDVRIPRNQMLMKNAQVLTDGTFVQGRPPLLLYGTMVYVRVITVKDVLFGLLQAATI-- 317
            .|.:.:..|.:|...:| .|...|. |.|  |......||            :.:|:|.||..  
  Rat   270 TGMIIMDSVEVPEENVL-PNVSSLA-GPF--GCLNTARYG------------ITWGVLGAAEFCL 318

  Fly   318 --ATRYSVVRRQSRINSDQPEVSVLDHITQQ--AKILPQIARGVSYRLVSDWLWRFYEDVLRQLE 378
              |.:|::.|.|..:...:      :.:.|:  |.:|.:|..|:...|           .|.:|:
  Rat   319 HTARQYALDRIQFGVPLAR------NQLVQKKLADMLTEITLGLHACL-----------QLGRLK 366

  Fly   379 DESTKGRNSLPELHAL---SCCLKAVATDEASEGVDLLRKSCGGHGFLS-------SANFDSIYG 433
            |:.    .:.||:.:|   :.|.||:  |.|.:..|:|    ||:|...       :.|.:    
  Rat   367 DQD----KATPEMVSLLKRNNCGKAL--DIARQARDIL----GGNGISDEYHVIRHAMNLE---- 417

  Fly   434 LTAATYTYEGEYTVLLLQTAR 454
               |..||||.:.:..|...|
  Rat   418 ---AVNTYEGTHDIHALILGR 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4586NP_572371.1 ACAD 6..653 CDD:299127 102/476 (21%)
PLN02443 7..677 CDD:178062 102/476 (21%)
GcdhNP_001102366.1 GCD 57..443 CDD:173840 98/462 (21%)
CaiA 69..443 CDD:224871 94/447 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.