Protein Alignment CG4586 and Acox2

DIOPT Version :10

• Sequence 1: NP_572371.1
• Gene: CG4586 / 31641
• FlyBaseID: FBgn0029924
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_665713.2
• Gene: Acox2 / 252898
• RGDID: 628684
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 247/717 - (34%)
• Similarity: 368/717 - (51%)
• Gaps: 102/717 - (14%)

  Fly     3 VNADLQRERAAATLDSEDFARWWAGGSGQLEERRALERRFYEDPDF-AEPVHPSCLSYKERYEQT 66
            |:.|:..||.:.:...|.......||......||.:|.....||.| .:.::  .::.:|.||..
  Rat    18 VHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDPVFNLKKLY--FMTREELYEDA 80

  Fly    67 VARSTRFLAKLRQWQ---REKQPQLQLSVNMLRDFRLLLSGSLGTGLFQQSFPLRVHFSMFMTTL 128
            :.:  ||..:...|.   .|..|: ::..|.:.|..:.||               :| .:.|..:
  Rat    81 IQK--RFHLEKLAWSLGWSEDGPE-RIYANRVLDGNVNLS---------------LH-GVAMNAI 126

  Fly   129 LSQGTEEQQAQW--LNRSWHMDGVLGTYAQTELGHGTFVRGLETRADYDPITQEFILNTPTQSSY 191
            .|.|::||.|:|  |.:::.   ::.|||||||||||:::||||.|.||...|||::::||.:|.
  Rat   127 RSLGSDEQIAKWGQLCKNFQ---IITTYAQTELGHGTYLQGLETEATYDEARQEFVIHSPTMTST 188

  Fly   192 KWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGGNGVNNG 256
            |||||.||.:...|:|||||...|..:|:.:|:|.||....|.||.|:.||||||::|...::||
  Rat   189 KWWPGDLGWSVTHAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGLEHIDNG 253

  Fly   257 FLGLRDVRIPRNQMLMKNAQVLTDGTFVQGRPPLLLYGTMVYVRV-ITVKDVLFGLLQAATIATR 320
            ||.|..||:||..||.:.|:||.|||:.:...|...|..|:..|| :..|.:|..|.:|..||||
  Rat   254 FLQLNHVRVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLCKGILPSLQKACIIATR 318

  Fly   321 YSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRL------VSDWLWRFYEDVLRQLED 379
            |||:|.|||:....||..:|::.|||.|:|||:|  |||..      :|::....|..:|::  |
  Rat   319 YSVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLA--VSYAFHFTATSLSEFFHSSYSAILKR--D 379

  Fly   380 ESTKGRNSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGE 444
            .|.     ||||||||..:||...|..::|.::.|::|||||:...:...::.....|:.|||||
  Rat   380 FSL-----LPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGE 439

  Fly   445 YTVLLLQTARFLVRQYAD------SLKRKVLPSSVSYLR------------------DTARLIW- 484
            .|||.||.||||::.|..      :..:|.||.||.|:.                  |.....|
  Rat   440 NTVLYLQVARFLMKSYLQAQASPGATPQKPLPQSVMYIATQRPARCSAQTAADFRCPDVYTTAWA 504

  Fly   485 --GKNLV---ANCVRALEISAMEQVRDAW-QTQKMHQSGKVSPEMASNLAGRQLTSAAIAHAHAF 543
              ...|:   |:..:.|..|.::| .||| ||..:|                  ..||.|:.:..
  Rat   505 YVSTRLIRDAAHRTQTLMKSGVDQ-HDAWNQTTVIH------------------LQAAKAYCYFI 550

  Fly   544 FTRNALEQVEALRKKGDLSPNVSLILGQLVELFVIDTFLRQSGCVLRWNNGITGTQLRFVERRFE 608
            ..:|..|.||.|    |..|.:..:|.:|.:|:.:...|..||..|. :..::|.|:......|.
  Rat   551 TVKNFKEAVEKL----DKEPEIQRVLQRLCDLYALHGVLTNSGDFLH-DGFLSGAQVDMAREAFL 610

  Fly   609 ELLAKLRPNAVALVDGFDFHDRVLGSTLGCHDGRVYERLMEEARRNPINQEPVNSSFHNHLLPMM 673
            :||..:|.:|:.|.|.|||.|..|.|.|||:||.|||||.|.|:::|.|.:. |.::..::.|:|
  Rat   611 DLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKSPANTQE-NPAYKKYIRPLM 674

  Fly   674 RG 675
            .|
  Rat   675 LG 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4586	NP_572371.1	ACAD	6..653	CDD:447864	240/690 (35%)
Acox2	NP_665713.2	AXO	20..655	CDD:173839	240/691 (35%)
		Microbody targeting signal. /evidence=ECO:0000255	679..681