DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4586 and Acads

DIOPT Version :9

Sequence 1:NP_572371.1 Gene:CG4586 / 31641 FlyBaseID:FBgn0029924 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_031409.2 Gene:Acads / 11409 MGIID:87868 Length:412 Species:Mus musculus


Alignment Length:492 Identity:106/492 - (21%)
Similarity:182/492 - (36%) Gaps:126/492 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 AAATLDSEDFARWWAGGSGQLEERRALE----RRFY------EDPDFAEPVHPSCLSYKERYEQT 66
            |||.|         |...|.|  ||||.    ||.:      |.|:..:.:..:|..:.|:....
Mouse     2 AAALL---------ARARGPL--RRALGVRDWRRLHTVYQSVELPETHQMLRQTCRDFAEKELVP 55

  Fly    67 VARSTRFLAKLRQWQREKQ-PQLQLSVNMLRDFRLL-------LSGS------------------ 105
            :|         .|..||.. |..|  |..:.:..||       |||:                  
Mouse    56 IA---------AQLDREHLFPTAQ--VKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRAC 109

  Fly   106 LGTGLFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNRSWHMDGVLGTYAQTELGHGTFVRGLET 170
            ..||:.     :.|:.|:::..:|..|:.:|:.||:....:.|.: |.:|.:|.|:|:......|
Mouse   110 ASTGVI-----MSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKI-GCFALSEPGNGSDAGAAST 168

  Fly   171 RADYDPITQEFILN-TPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHE 234
            .|..:  ...::|| |....:..|       .|:..:|.|......::.|:.:|:|.:       
Mouse   169 TAREE--GDSWVLNGTKAWITNSW-------EASATVVFASTDRSRQNKGISAFLVPM------- 217

  Fly   235 PLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQMLMKNAQVLTDGTFVQGRPPLLLYGTMVYV 299
            |..|:.:|....:||....:...|...|.|||:..:|              |.|.:   |..:.:
Mouse   218 PTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLL--------------GEPGM---GFKIAM 265

  Fly   300 RV-----ITVKDVLFGLLQAA-TIATRYSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVS 358
            :.     |.:.....|:.||: ..|.:|:..|     |:....::.|.:|  |.|:........|
Mouse   266 QTLDMGRIGIASQALGIAQASLDCAVKYAENR-----NAFGAPLTKLQNI--QFKLADMALALES 323

  Fly   359 YRLVSDWLWRFYEDVLRQLEDESTKGRNSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFL 423
            .||:: |.....:|..:....||...:.:..|          .||..:.:.:.:|    ||.|::
Mouse   324 ARLLT-WRAAMLKDNKKPFTKESAMAKLAASE----------AATAISHQAIQIL----GGMGYV 373

  Fly   424 SSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQY 460
            :....:..|.....|..|||...:..|..|..|:|.|
Mouse   374 TEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSY 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4586NP_572371.1 ACAD 6..653 CDD:299127 106/492 (22%)
PLN02443 7..677 CDD:178062 106/492 (22%)
AcadsNP_031409.2 SCAD_SBCAD 36..408 CDD:173847 89/443 (20%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P15651 269..272 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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