DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Setd3 and AT3G07670

DIOPT Version :9

Sequence 1:	NP_727144.1	Gene:	Setd3 / 31638	FlyBaseID:	FBgn0052732	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_187424.1	Gene:	AT3G07670 / 819958	AraportID:	AT3G07670	Length:	504	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	117/515 - (22%)
Similarity:	210/515 - (40%)	Gaps:	107/515 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 YGQLQELLKQIMILE-EPLSQAVC---------------------PQIS-----DSPDDQTRLAK 117
            |..|.:|..|.:.|. .||..:.|                     |:||     ||.::.|.|..
plant    15 YSPLHKLRNQNITLSFSPLPLSRCRPGIHCSVSAGETTIQSMEEAPKISWGCEIDSLENATSLQN 79

  Fly   118 VEAFSAWAKDGGVHSEGLEIAIFPGYQLGLRATRPLAKDELVLSVPRKLILSEENNSDCRLFGKM 182
                  |..|.|:..:.:.|......:.||.|::.|.|.|.:|.||..|::|.::.......|::
plant    80 ------WLSDSGLPPQKMAIDRVDIGERGLVASQNLRKGEKLLFVPPSLVISADSEWTNAEAGEV 138

  Fly   183 TQATHLN----LAYDLVIEKIRGEFSEWRPYIDVLPAKYNTVLYFTTKQMEL-LRGTAAAALAMR 242
            .:...:.    ||..|:.|....:.|.|..||..||.:..::||:|..:::: |..:.....|:.
plant   139 MKRYDVPDWPLLATYLISEASLQKSSRWFNYISALPRQPYSLLYWTRTELDMYLEASQIRERAIE 203

  Fly   243 QCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCY-------KLYRWAVSTVMTRQ 300
            :...:...|..|                    |...|::|...:       :.::|:...:.:|.
plant   204 RITNVVGTYEDL--------------------RSRIFSKHPQLFPKEVFNDETFKWSFGILFSRL 248

  Fly   301 NLVPSEKQESEDGPKLISALIPYWDMANHRPGKITSF--YATVSRQLECTAQEAVNTGEQFFIYY 363
            ..:|     |.||.   .||:|:.||.||. .::.:|  |...|:.:..|.......|||.||.|
plant   249 VRLP-----SMDGR---FALVPWADMLNHN-CEVETFLDYDKSSKGVVFTTDRPYQPGEQVFISY 304

  Fly   364 GDRSNTDLLVHNGFV--DPNNTKDYVNIRVGLSLTDALAAKRASILDK--LNIRHTAELRVLPAP 424
            |::||.:||:..|||  :..|..|.|.:.:.|...|....::...|.|  |:......:|:...|
plant   305 GNKSNGELLLSYGFVPREGTNPSDSVELALSLRKNDKCYEEKLDALKKHGLSTPQCFPVRITGWP 369

  Fly   425 DFISKELLAFVRV------FKMSAEQLDHWCSD-LDRAGDLLHIDCALETDHETRTWQFLEDRLK 482
                .||:|:..:      .:.:.|::....|: .....||.:.:  :|.|    ..||:.|..:
plant   370 ----MELMAYAYLVVSPPDMRNNFEEMAKAASNKTSTKNDLKYPE--IEED----ALQFILDSCE 424

  Fly   483 LLLAVFNKEMHEADEVKELELKDGQEIELMLFLYRRL-------ERSILAGALQYAQEHR 535
            ..::.:::.:.|:..: :|::...:::....|| ::|       ||.||..| ||....|
plant   425 TSISKYSRFLKESGSM-DLDITSPKQLNRKAFL-KQLAVDLSTSERRILYRA-QYILRRR 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Setd3	NP_727144.1	SET_SETD3	119..378	CDD:380953	65/272 (24%)
Setd3	NP_727144.1	Rubis-subs-bind	400..524	CDD:370401	24/139 (17%)
AT3G07670	NP_187424.1	SET_RBCMT	84..319	CDD:380956	63/263 (24%)
AT3G07670	NP_187424.1	Rubis-subs-bind	343..471	CDD:401276	24/139 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	50	1.000	Domainoid score	I4376
eggNOG	1	0.900	-	-		E1_KOG1337
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I2455
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489371at2759
OrthoFinder	1	1.000	-	-		FOG0001685
OrthoInspector	1	1.000	-	-		otm2928
orthoMCL	1	0.900	-	-		OOG6_101154
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730