DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Setd3 and AT2G18850

DIOPT Version :9

Sequence 1:	NP_727144.1	Gene:	Setd3 / 31638	FlyBaseID:	FBgn0052732	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_179475.3	Gene:	AT2G18850 / 816400	AraportID:	AT2G18850	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	470	Identity:	115/470 - (24%)
Similarity:	172/470 - (36%)	Gaps:	123/470 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 DQTRLAKVEAFSAWAKDGGVHSEGLEIAIFPGYQLGLRATRPLAKDELVLSVPRKLILSEE--NN 173
            |..|..|......|.:|.||.:: |:||...||..|..|:..|...::.|.:|...|:|||  .|
plant   143 DSYRCEKESKLVEWGQDNGVKTK-LQIAQIDGYGRGAIASEDLKFGDVALEIPVSSIISEEYVYN 206

  Fly   174 SD----CRLFGKMTQATHLNLAYDLVIEKIRGEFSEWRPYIDVLPAKYNTVLYFTTKQMELLRGT 234
            ||    ...|..:|..|.|.|   ..:.:.....|:::||.|.|...:.|.|.|....:..|.||
plant   207 SDMYPILETFDGITSETMLLL---WTMREKHNLDSKFKPYFDSLQENFCTGLSFGVDAIMELDGT 268

  Fly   235 AAAALAMRQCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCYKLYRWAVSTVMTR 299
            ......|:...::.::|..|.        |...|........|:..:|      |.||.....:.
plant   269 LLLDEIMQAKELLRERYDELI--------PLLSNHREVFPPELYTWEH------YLWACELYYSN 319

  Fly   300 QNLVPSEKQESEDGPKLISALIPYWDMANH-------RPGKI----TSFYATVSRQLECTAQEAV 353
                 |.:.:..|| ||.:.|||.....||       :.||:    :|....|||  .|
plant   320 -----SMQIKFPDG-KLKTCLIPVAGFLNHSIYPHIVKYGKVDIETSSLKFPVSR--PC------ 370

  Fly   354 NTGEQFFIYYGDRSNTDLLVHNGFVDPNNTKDYVNIRVGLSLTD-----------ALAAKRASIL 407
            |.|||.|:.||:.|::.||...||: |.....|..|.:...:.|           ....:...:.
plant   371 NKGEQCFLSYGNYSSSHLLTFYGFL-PKGDNPYDVIPLDFDVIDDEDIETEFSWTTHMLRGTWLS 434

  Fly   408 DKLNIRHTAELRVLPAPDFISKELLAFVRVFKMSAEQLDHWCSDLDRAGDLLHIDCALETDHETR 472
            ...||.|..    ||.|      ||.::|                 :|..|:|       ..||.
plant   435 SNHNIFHYG----LPTP------LLNYLR-----------------KAHGLVH-------HSETD 465

  Fly   473 TWQFLEDR---LKLLLAVFNKEMH---EADEVKE----------LELKDGQEIELMLFLYRRLER 521
            .|:.||..   |:.|.:.|:..|.   :||.:..          :|.|:.|         |::..
plant   466 LWKNLEVEIGVLENLQSTFDDMMQNLGDADSIDRENADWDVKLAMEFKERQ---------RKIVS 521

  Fly   522 SIL---AGALQYAQE 533
            |||   :..::..||
plant   522 SILDSCSAGIKLVQE 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Setd3	NP_727144.1	SET_SETD3	119..378	CDD:380953	75/275 (27%)
Setd3	NP_727144.1	Rubis-subs-bind	400..524	CDD:370401	28/139 (20%)
AT2G18850	NP_179475.3	SET_LSMT	165..395	CDD:380925	71/261 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910