Protein Alignment Setd3 and setd4

DIOPT Version :9

• Sequence 1: NP_727144.1
• Gene: Setd3 / 31638
• FlyBaseID: FBgn0052732
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001039027.1
• Gene: setd4 / 564058
• ZFINID: ZDB-GENE-050808-2
• Length: 440
• Species: Danio rerio
• Alignment Length: 439
• Identity: 122/439 - (27%)
• Similarity: 178/439 - (40%)
• Gaps: 76/439 - (17%)

  Fly   124 WAKDGGVHSEGLEIAIFPGYQLGLRATRPLAKDELVLSVPRKLILSEENNSDCRLFGKMTQATH- 187
            |..:.|..|:.|....|.....||.||:.:.....|:|:|.:.:|:...      ..|...|.:
Zfish    40 WLNERGFTSQSLIPVNFHDTGRGLMATQTIKAKNSVISLPEECLLTTST------VLKSYMADYI 98

  Fly   188 ----------LNLAYDLVIEKIRGEFSEWRPYIDVLPAKYNTVLYFTTKQMELL-RGTAAAALAM 241
                      |.|...|:.|:..||.|||.||||:||..|...|||....:||| |.....|...
Zfish    99 KRWHPPISPLLALCCFLISERHHGEASEWNPYIDILPKTYTCPLYFPDNVIELLPRSLQKKATQQ 163

  Fly   242 RQCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCYKLYRWAVSTVMTRQNLVPSE 306
            ::      |:..|:..:.|.........:.|.|.  .|:|..|     |||..:|.||...:..:
Zfish   164 KE------QFQELFSSSQTFFHSLQPLFNQPTEE--LFSQDAL-----RWAWCSVNTRTVYMEHD 215

  Fly   307 KQESEDGPKLISALIPYWDMANHRPGKITSFYATVSRQLECTAQEAVNTGEQF---FIYYGDRSN 368
            :.:.....|.:.||.||.|:.||.|.  ....|..:::..|....:||..::|   ||.||...|
Zfish   216 QSKYLSREKDVYALAPYLDLLNHCPN--VQVEAGFNKETRCYEIRSVNGCKKFQQAFINYGPHDN 278

  Fly   369 TDLLVHNGFVDPNNTK-----DYVNIRVGLSLTDALAAKRASILDKLNIRHTAELRVLP-APDFI 427
            ..||:..|||.|.|..     |...::|||...|....::.     |.::....||.|. ..|..
Zfish   279 HRLLLEYGFVAPCNPHSVVYVDLETLKVGLDEKDKQLKEKL-----LYLKDNDFLRNLTFGMDGP 338

  Fly   428 SKELLAFVRVFKMSAEQLDHWCSDLDRAGDLLHIDCALETDHETRTWQFLEDRLKLLLAVFNKEM 492
            |..|:..:|:..:..:|...|.|.|        :..|:..|.|  .| .:|..|||.     ..:
Zfish   339 SWRLMTALRLLSLKPQQYTRWKSVL--------LGAAVSQDRE--DW-CIESALKLC-----NNL 387

  Fly   493 HEADEVKELE----LKDGQE---IELMLFL--YRRLERSILA---GALQ 529
            .| |.||.||    ||:|..   :|.:..:  .||.|::||.   |.||
Zfish   388 TE-DNVKALERLAQLKEGANQSGLEQLCVVESLRREEQNILGHTRGLLQ 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Setd3	NP_727144.1	SET_SETD3	119..378	CDD:380953	75/268 (28%)
		Rubis-subs-bind	400..524	CDD:370401	33/133 (25%)
setd4	NP_001039027.1	Rubis-subs-bind	313..427	CDD:286371	33/135 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1337
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840