Protein Alignment Setd3 and setd6

DIOPT Version :9

• Sequence 1: NP_727144.1
• Gene: Setd3 / 31638
• FlyBaseID: FBgn0052732
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001096520.1
• Gene: setd6 / 100125156
• XenbaseID: XB-GENE-998235
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 469
• Identity: 110/469 - (23%)
• Similarity: 170/469 - (36%)
• Gaps: 112/469 - (23%)

  Fly   118 VEAFSAWAKDGG--------VHSEGLEIAIFPGYQLGLRATRPLAKDELVLSVPRKLILSEENNS 174
            |..|.||.|..|        :.:||..      .|.|:.|...|:..||:.|:||..|||:....
 Frog    22 VSCFLAWCKKVGLELNPKVYISTEGTV------SQYGMLAREDLSDGELLFSIPRSAILSQNTTR 80

  Fly   175 DCRLFGKMTQATH---------LNLAYDLVIEKIRGEFSEWRPYIDVLP---AKYNTVLYFTTKQ 227
            ...|..|...:..         ::|.|:..     ...|.|.||..:.|   .....:.:...:|
 Frog    81 IRDLIEKEQDSLQSCSGWVPLLISLLYEAT-----DSSSHWAPYFGLWPELDPPDMPMFWSEEEQ 140

  Fly   228 MELLRGTAAAALAMRQCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCYKLYRWA 292
            .:||:||.......:..:.|.|:|       :::..|..  |.:|.:    |........||:..
 Frog   141 TKLLQGTGILEAVHKDLKNIEKEY-------NSIVLPFI--RRNPEK----FCPMKHTLDLYKRL 192

  Fly   293 VSTVMTRQNLVPSEKQESEDGPK--LISALIPYWDMANHRPGKITSFYATVSRQLEC---TAQEA 352
            |:.||......|.|:.|.||..|  |...::|..|:.||    :....|.:....||   ...::
 Frog   193 VAFVMAYSFQEPQEEDEEEDIEKDILPPMMVPVADLLNH----VAQHNAHLEFTPECLRMITTKS 253

  Fly   353 VNTGEQFFIYYGDRSNTDLLVHNGFVDP-----NNTKD--YVNIR-----VGLSLTDAL-AAKRA 404
            |..|::.|..||..:|..||...||.:|     |.|.|  .|.:|     |..:..|.| ..||.
 Frog   254 VCAGQELFNTYGQMANWQLLHMYGFAEPHPQNCNETADIQMVTVREAAFQVARTEEDRLEMQKRW 318

  Fly   405 SILDKLNIRHTAELRVLPAPDFIS-KELLAFVRVFKMSAEQL------DHWCSDLDRAGD----- 457
            ..|..:.|.......|....:.:: :||.|.::|..||.::.      |.|..|.|....
 Frog   319 DFLCHIEIVGEEGAFVFGLEEVMTEEELKACLKVLCMSTDEFAEYKENDGWEEDEDNDEQTLLTQ 383

  Fly   458 -----------LLHIDCALETDHETRTWQFLEDRLKLLLAVFN----------KEMHEADEVKEL 501
                       |||:...|       |.:..:..|.:..|:.|          :|.|      .|
 Frog   384 EISRLPIPWRKLLHLSAEL-------TLKAYKTELSMDEALVNDPTAYAKLSSREQH------SL 435

  Fly   502 ELKDGQEIELMLFL 515
            :::.||:..|.|.|
 Frog   436 QVQYGQKKILHLLL 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Setd3	NP_727144.1	SET_SETD3	119..378	CDD:380953	68/283 (24%)
		Rubis-subs-bind	400..524	CDD:370401	31/149 (21%)
setd6	NP_001096520.1	SET	<225..265	CDD:307139	9/43 (21%)
		Rubis-subs-bind	314..445	CDD:312693	28/143 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940