DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and Cht4

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	124/410 - (30%)
Similarity:	191/410 - (46%)	Gaps:	87/410 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LRTLVCWSALLFSLLCLCLGFIGLGLLGIQTGEVHKVGQRLVCYYAS-------DGTHNLSLLDV 86
            ::.:..|:   .:.||||||         |.....|:   |.||:.:       ||....|  |:
  Fly     1 MKLVSIWA---LAALCLCLG---------QVASSEKL---LNCYWGTWANYRPGDGKFTPS--DI 48

  Fly    87 PGDLCTHIN-----IGPA----TLDNATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSG 142
            ...|||||:     |..|    :|| ..:.:.|.|..:.|  |.:.:..:|.:.:|..:||.:.|
  Fly    49 DPSLCTHISYTFFGISDAGEFKSLD-TWLDMDDGLGFISQ--TIALKQRNPNLKILAVVGGWNEG 110

  Fly   143 RS-FALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFP-----SAYDRERMHLSQLLYEIRT 201
            .: ::.|.|:.|.|..|:.:....::.| |.||:|||||:|     |..|||  :...||.||
  Fly   111 STKYSAMAADPAKRATFVSTSLAFIQQY-SFDGLDLDWEYPGQRGGSEADRE--NFVTLLREI-- 170

  Fly   202 EWRREKRTND----ILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAP 262
                 |.|.|    .|.:||.|.|..|..:|||..|:.:..::|:|:||||...:.  :.|||||
  Fly   171 -----KETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDG--YLGLNAP 228

  Fly   263 LYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCG 327
            |.            .:..::.:||..|...::|::|:..||||:.:.:...:..||...|.|..|
  Fly   229 LP------------EVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAG 281

  Fly   328 ----QLGFTTLTETC----ECVTKFFKPNLSYDAESCSPYLSALQEWISYENQTSIACKANYVKS 384
                :.||....|.|    :.|         :|.|:.:||.....:||.|:|..||..|...|:|
  Fly   282 VYTRENGFLGYHEICLNNWQTV---------FDQENGAPYAFQGDQWIGYDNPESIQLKMQLVES 337

  Fly   385 LNLGGVMVFSLNTDDLKNSC 404
            .||||.|::|:.|||.:..|
  Fly   338 RNLGGAMMWSIETDDFRGLC 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	111/363 (31%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	115/370 (31%)
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	115/370 (31%)
		Glyco_18	28..351	CDD:214753	110/360 (31%)
		CBM_14	421..462	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920