DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and chia.1

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	410	Identity:	121/410 - (29%)
Similarity:	195/410 - (47%)	Gaps:	64/410 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GLG-LLGIQTGEVHKVGQRLVCYYASDGTHNLSLLDVPGD-----------LCTHINIGPATL-- 101
            ||| ||.:|...    ..:||||..:...:.      ||:           ||||:....||:
Zfish     9 GLGILLSLQIVS----STKLVCYMTNWSQYR------PGNGKFLPENIDPFLCTHVVYALATISY 63

  Fly   102 DN--ATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSGRS-FALMVANHAMRKLFLRSLR 163
            ||  .||...|.   .|.......:..:|.:...|.:||..:|.| :..|||....||.|:|:..
Zfish    64 DNQITTIEWNDV---DLYKSMNELKKVNPALKTQLSVGGLVNGVSPYINMVATPENRKAFIRNAL 125

  Fly   164 EILRTYPSLDGIDLDWEFP---SAYDRERMHLSQLLYEIRTEWRRE----KRTNDILSLAVAAPE 221
            ..||.: ..||:|:||::|   .:..:::..|:..:.|:|....:|    |:|..:||:.|:|.:
Zfish   126 LFLRLH-EFDGMDIDWQYPGHNGSPPQDKQRLTTFIKEMRDAIEQEAIDTKKTPLLLSIKVSAIK 189

  Fly   222 GIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWL 286
            .....||:.:|:....|:|.:||||:|.:.:  |.||.|:||:..|.:...:...|||.::::||
Zfish   190 TTIENAYEAKEVASLVDFVTIMSYDYHGHWD--PITGHNSPLFRSSFDTGSIVHHNINSSLEFWL 252

  Fly   287 KSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCG----QLGFTTLTETCECVTKFFKP 347
            .||....||::||||||.:| :::.....:||||:|....|    :.||.:..|.|...:..
Zfish   253 GSGAPADRLLLGLPTYGRTF-MLSTSQTGLGAPANGPADAGPYTREAGFWSYYEICPMESSV--- 313

  Fly   348 NLSYDAESCSPYLSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDD------------- 399
            .:.:..|...||....:.|:.::||.||..|..::.||.|||..|::|:.||
Zfish   314 PIHWIDEQMVPYAVQGRAWVGFDNQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPL 378

  Fly   400 ---LKNSCSIMPNLKYSEKP 416
               |:||....|....:.:|
Zfish   379 VNHLRNSLGFPPKPTTTPRP 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	108/356 (30%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	115/391 (29%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	108/356 (30%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	112/377 (30%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930