DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht11 and Cht8

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	122/429 - (28%)
Similarity:	205/429 - (47%)	Gaps:	65/429 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 WSALLFSLLCLCLGFIGLGLLGIQTGEVHKVGQRLVCYYAS-----DGTHNLSLLDVPGDLCTHI 94
            ||  :..|:.|.||.|   |:...:.......:.:|||..:     .|.....:.|:...||||:
  Fly     2 WS--VSGLVKLLLGVI---LMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHL 61

  Fly    95 --------NIGPATLDNATIVLPDTLRQVLQNDTRSFRA---AHPQVHLLLWIGGADSG-RSFAL 147
                    ..|...:.:|.:.|.:...   :.:.:||.|   .:|.:..|:.:||.:.| :.|:|
  Fly    62 IYAFLGIEETGQLRVIDAYLDLEENSG---RGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSL 123

  Fly   148 MVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFP----SAYDRERMHLSQLLYEIRTEWRREKR 208
            :..:.:.|:.|:..:...|:.: ..||:|||||:|    |..:.:|.:....|.|::   ...:.
  Fly   124 VARDPSKREKFVDDVVRFLQRH-GFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELK---EGLEP 184

  Fly   209 TNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPF---TGLNAPLYARSQER 270
            ...|||.||.:.:..|..:|||..:..|.|.:|:|:||.|     .|:   .|:||||||..::.
  Fly   185 FGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLH-----GPWDQVVGINAPLYAAEKDA 244

  Fly   271 S----LMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCGQ--- 328
            |    .....|::..|::|||:|...::|::|:|.||.||||.....::.|||..|.|..|.
  Fly   245 SDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSR 309

  Fly   329 ----LGFTTLTETCECVTKFFKPNLSYDAESCSPYLSALQEWISYENQTSIACKANYVKSLNLGG 389
                ||:   .|.||.:.: .:....::|....||....::|:.||:..|:|.||.||...:|||
  Fly   310 EPGVLGY---NELCEMMER-EEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGG 370

  Fly   390 VMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAIKDIL 428
            :|::||.:||.:.:|...|         :||...|..:|
  Fly   371 IMIWSLESDDFRGTCGQQP---------YPLLHEINRVL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	106/364 (29%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	113/393 (29%)
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	113/393 (29%)
		Glyco_18	31..379	CDD:214753	106/363 (29%)
		CBM_14	424..476	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920