DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and chia.6

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_955897.2	Gene:	chia.6 / 322420	ZFINID:	ZDB-GENE-030131-1140	Length:	480	Species:	Danio rerio

Alignment Length:	391	Identity:	109/391 - (27%)
Similarity:	186/391 - (47%)	Gaps:	37/391 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 VGQRLVCYYASDGTHNLSL-----LDVPGDLCTHINIGPATLDNAT-IVLPDTLRQVLQNDTRSF 123
            :..:||||:.:...:...:     .:|...||||:....:.::|.. :...:...:.|.......
Zfish    19 LASQLVCYFTNWSQYRPDVGKYMPSNVDPHLCTHLIYAFSIINNENKLTTYEWNDETLYQSFNGL 83

  Fly   124 RAAHPQVHLLLWIGGADSGRS-FALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPSA--- 184
            :.::|.:..||.:||.:.|.: |:.||:....|:.|::|....|||: ..||:|||||:|.:
Zfish    84 KQSNPNLKTLLAVGGWNFGTTQFSSMVSTPQNRQTFIQSSITFLRTH-GFDGLDLDWEYPGSRGS 147

  Fly   185 --YDRERMHL--SQLLYEIRTEWRREKRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSY 245
              .|::|..|  .:|:...:.|.....|...:|:.||||.:|.....|:|.||..|.|::|:|:|
Zfish   148 PPEDKQRFTLLCKELVEAYQAESAATGRPRLMLTAAVAAGKGNIDAGYEIAEIAKYLDFINIMTY 212

  Fly   246 DFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVN 310
            |||...|..  ||.|:|||..|.:......:|.::.:.:|...|...::|.:|...||.:|.|.:
Zfish   213 DFHGSWESV--TGHNSPLYRGSGDIGDKIYYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFRLSS 275

  Fly   311 PLNHRIGAPASGYGKCG----QLGFTTLTETCECVTKFFKPNLSYDAESCSPYLSALQEWISYEN 371
            .:: .:||||||....|    :.||.:..|.|   |...:..:....:...||.:..|||:.::|
Zfish   276 AVS-GVGAPASGAASAGTYTREAGFWSYYEIC---TFLKQATVQQIVDQKVPYATKGQEWVGFDN 336

  Fly   372 QTSIACKANYVKSLNLGGVMVFSLNTDDLKNS-CS-----------IMPNLKYSEKPVFPLTQAI 424
            ..|...|.:|:|....||..|::|:.||.... |.           .:.|:..:|.|..|.:..:
Zfish   337 MESYKTKVDYLKEKGFGGAFVWALDLDDFSGQFCGQSKYPLIGQLRTLLNINNTEFPYNPPSTTV 401

  Fly   425 K 425
            |
Zfish   402 K 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	101/347 (29%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	109/387 (28%)
chia.6	NP_955897.2	Glyco_18	22..363	CDD:214753	101/347 (29%)
		GH18_chitolectin_chitotriosidase	23..385	CDD:119351	104/368 (28%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830