DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and Cht12

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	92/350 - (26%)
Similarity:	158/350 - (45%)	Gaps:	74/350 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 LCTHINIGP---ATLDNATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLW---------IGG-ADS 141
            ||||:.:|.   ...|:..:.:.|.: .:|:.|..|      .|..:.|         ||| .:.
  Fly    51 LCTHLVLGSGIGVDGDSGELRITDKI-LLLEKDKLS------SVKTMKWDSIKKVMFTIGGWEED 108

  Fly   142 GRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPS---AYDRERMHLSQLLYEIRTEW 203
            ..||:.|||:...|..|..|:.|.:..: ..||:.:||.:|:   .:..:|.:...||.|:...:
  Fly   109 SSSFSRMVASPKKRDNFYSSMLEFMFRW-GFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIF 172

  Fly   204 RRE----------KRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPF-- 256
            |:.          :|.|.||.            :|:|.||..::|:::||.:|     |..|:
  Fly   173 RKNQLILMVAVLGRRDNRILE------------SYNIPEIVNHSDFIHLMMHD-----EQDPYHL 220

  Fly   257 -TGLNAPL--YARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGA 318
             ...||||  |..|...|:|          .|.::|..|::|::|:|.:..|||: :.....:|:
  Fly   221 RLAYNAPLVGYEGSVTDSIM----------HWKRNGGAPEKLILGIPLFVRSFTM-DRNQSTVGS 274

  Fly   319 PASGYGK----CGQLGFTTLTETCECVTKFFKPNLSYDAESCSPYLSALQEWISYENQTSIACKA 379
            ...|.|:    ..:.||.|..|.|...:|:.:   .:|..:..||.:...:|:||||..||..|.
  Fly   275 ACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSR---MFDQLAKVPYATRGDQWVSYENPRSIWAKM 336

  Fly   380 NYVKSLNLGGVMVFSLNTDDLKNSC 404
            :.::...|||.|.::::.||.:..|
  Fly   337 HLLQEHKLGGAMAWTIDVDDFRGRC 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	89/342 (26%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	91/349 (26%)
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	91/349 (26%)
		Glyco_hydro_18	47..355	CDD:279094	89/342 (26%)
		ChtBD2	394..438	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920