DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and lmd-4

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_504862.2	Gene:	lmd-4 / 179121	WormBaseID:	WBGene00017233	Length:	2011	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	96/362 - (26%)
Similarity:	184/362 - (50%)	Gaps:	37/362 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GQRLVCYYASDGTHNLSLLDVPGDLCTH-------------INIGPATLDNATIVLPDTLRQVLQ 117
            |:|:|.||...|...::...:  ...||             :..|..:.|::.........:...
Worm  1478 GKRIVGYYTGWGDREITENQL--KKLTHVIFAFVAMYEDGSVKFGAVSEDDSGPQAAKKAERRFL 1540

  Fly   118 NDTRSFRAAHPQVHLLLWIGGADSGRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFP 182
            |..:..|||:..|.:|..:||.|:.:.|:.:.|:...||.|:.|:...:.. ..:||:|||||:|
Worm  1541 NMKKKARAANSGVRVLFAVGGWDNSQYFSSVAADSGKRKKFVDSIASFVED-QKIDGVDLDWEYP 1604

  Fly   183 SAYDRERMHLSQLLYEIR---TEWRREKRTND--ILSLAVAAPEGIAFYAYDIREINLYADYVNL 242
            .:..::..:..||:.|||   :|..::|:..|  :::||.||.|......||::.|..|||::|:
Worm  1605 DSNGKDAKNHVQLIKEIREKFSEMAKKKKRKDPYVITLASAAGEWNLRKGYDLKGILKYADFINV 1669

  Fly   243 MSYDFHFYREDT--PFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHS 305
            |:||::...|..  .:||..||||..|. :......|.:::::::.....:|.:|.:|:|.||..
Worm  1670 MTYDYYGAWESKWGAYTGTPAPLYFGSL-KGFSGKLNADFSMKFYACKTEKPSQLNMGVPFYGRY 1733

  Fly   306 F-TLVNPLNH-----RIGAPASGYGKCGQLGFTTLTETCECVTKFFKPNLSYDAESCSPYL--SA 362
            : .::.|::.     |..||.:|..:.|.:|:..|.:     ..:.|.:.|:..::.:||:  :.
Worm  1734 WKNVLGPIDKSDNMWRTAAPQNGKYEGGYVGWRNLAK-----EGWNKGSASWHEKTKTPYIMNNG 1793

  Fly   363 LQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDD 399
            .::::.:||:.|:..|..|....||||:|:::|:.||
Worm  1794 AKKFLGFENERSLKEKMKYATDRNLGGLMIWALDLDD 1830

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	93/357 (26%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	94/359 (26%)
lmd-4	NP_504862.2	LysM	25..65	CDD:197609
		LysM	79..120	CDD:197609
		LysM	142..185	CDD:197609
		LysM	209..250	CDD:197609
		LysM	270..313	CDD:197609
		LysM	334..377	CDD:197609
		LysM	401..444	CDD:197609
		LysM	469..509	CDD:197609
		LysM	550..590	CDD:197609
		LysM	635..678	CDD:197609
		LysM	710..750	CDD:197609
		LysM	760..802	CDD:197609
		LysM	876..919	CDD:197609
		Self-incomp_S1	1359..1433	CDD:283566
		Glyco_18	1480..1825	CDD:214753	92/353 (26%)
		GH18_chitinase-like	1481..1824	CDD:299167	91/351 (26%)
		ChtBD1_GH18_2	1873..1924	CDD:211315
		ChtBD1_GH18_2	1951..2002	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810