DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and cht-3

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_501082.2	Gene:	cht-3 / 177464	WormBaseID:	WBGene00016084	Length:	1067	Species:	Caenorhabditis elegans

Alignment Length:	429	Identity:	83/429 - (19%)
Similarity:	156/429 - (36%)	Gaps:	90/429 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FIGLGL-----------LGIQTGEVHKVGQRLV--------------CYYASDGTHNLSLLD-VP 87
            |.|:|:           .|......|::...|:              ||...:.......:| :.
Worm   329 FAGIGISHALFDDPRGDCGTDPLPAHRLVMELIRNTIPANPAKCTRLCYLDPEEVEETFPIDNLK 393

  Fly    88 GDLCTHINIGPATLDNATIVLPDTLRQVLQNDTRSFRAAHPQV--HLLLWIGGADSGRSFALMVA 150
            .|.|:||.:....||.:..::.:...:.|......:|:...:|  .|:|.:|...:...:..::.
Worm   394 SDYCSHIVVPYFALDLSDKMIEEDKAEDLVKKIDDWRSKIVEVAPRLILSVGSKQASTIWQFLLG 458

  Fly   151 NHAMRKLFLRSLREILRTYPSLDGIDLDW-EFPSAYDRERMHLSQLLYEIRTEWRREKRTNDILS 214
            |...||.....|.:.:.: .:.||:::.| ..|...|.::.:|...:.:|..     ..|..::.
Worm   459 NDFHRKELAEGLVKAINS-TNADGLEISWTSQPMVSDFDKKNLKSFINDIVA-----ADTAKMVE 517

  Fly   215 LAVAAPEGIAFY-AYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNI 278
            :.||..:..|:. .||...:|..|..:.|.|:..|  .:..||||..:||.|.|.        ..
Worm   518 IVVATSQQSAYSDFYDYEHLNKTASLIVLHSHRLH--SDSLPFTGHPSPLRATSS--------MT 572

  Fly   279 NYTVQW------WLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCGQLGFTTLTET 337
            |..:.|      |::..:.|.:||:.|.....|...:..:......|      .||..|.::..:
Worm   573 NQKMSWESLLSHWVEKRVLPSKLVLSLSASTLSMQSLADVRSSAATP------FGQSAFVSMLRS 631

  Fly   338 CECVTKFFKPNLSYDAESCS-----------------PYLSALQEWISYENQTSIACKANYVKSL 385
                   .|.::....|.|.                 |||....:.::|||..|...||.:....
Worm   632 -------KKGDIHSQQEICESLKSGTGVTHWVDGAEVPYLRRYDQMVAYENTRSAHIKAVWASME 689

  Fly   386 NLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAI 424
            .:||:.:.:::.||        |:.....:..||:..|:
Worm   690 GVGGLALHNMHQDD--------PSAVCDNRTAFPILNAL 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	72/371 (19%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	78/398 (20%)
cht-3	NP_501082.2	Glyco_18	51..334	CDD:214753	2/4 (50%)
		GH18_chitinase-like	51..>103	CDD:299167
		Glyco_18	375..702	CDD:214753	71/355 (20%)
		GH18_chitinase-like	387..723	CDD:299167	75/371 (20%)
		Glyco_hydro_18	761..1043	CDD:279094
		GH18_chitinase-like	<1018..1062	CDD:299167
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4712
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760