DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht11 and cht-2

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_495798.2	Gene:	cht-2 / 174363	WormBaseID:	WBGene00011757	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	402	Identity:	96/402 - (23%)
Similarity:	180/402 - (44%)	Gaps:	54/402 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VCWSALLFSLLCLCLGFIGLGLLGIQTGEV--HKVGQRLVCYYASDGTHNLSLLDVPGDLCTHIN 95
            |.|..:||               |:..|.:  ...|:|.|.|..|.|.|  ...|...:..||:.
Worm    11 VVWITVLF---------------GVSNGGILDRSCGRRRVGYITSWGKH--PFRDDQAEKLTHLV 58

  Fly    96 IGPATLD-NATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSGRSFALMVANHAMRKLFL 159
            .....:| :.::.|.....:......:...:.||.:.||..:||.::.:.|:::.|:|:.|.:.:
Worm    59 FAFFVVDSDGSVKLEGDAAKARLEHVKEVASRHPDLKLLYAVGGWENSQYFSVLTADHSRRSILI 123

  Fly   160 RSLREILRTYPSLDGIDLDWEFP------SAYDRERMHLSQLLYEIRTEWR---REKRTNDILSL 215
            .:..::::.| ..||:|:|||:|      .....:|.:...|:.|:|.|.|   .|...:.::|.
Worm   124 SNFVKVIKEY-GFDGVDIDWEYPVTGGAVEGTPADRRNYVNLMRELRNELRDLESETGKSYLISF 187

  Fly   216 AVAAPEGIAFYAYDIREINLYADYVNLMSYDFH--FYREDTPFTGLNAPLYARSQERSLMATFNI 278
            |.||...:....||::::..|.|:||:||||:.  :..:...:||..|||.. :..:......|:
Worm   188 AGAAGHWVLKPGYDLQQLMKYCDFVNVMSYDYFGAWASKWGAYTGPPAPLQF-AMPKKFSGRMNV 251

  Fly   279 NYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPL------NHRIGAPASGYG---KCGQLGFTTL 334
            :.|::.:........::.:|:|.||..:..|...      ..|.....:..|   :.|.:.:..|
Worm   252 HATMKDYSCQIKATDKINMGVPFYGRFWKNVGDAVDSTDDMWRTATATNSEGTKFEGGDVQWRDL 316

  Fly   335 TETCECVTKFFKPNLSYDAESCSPY--LSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNT 397
            .|      ||......:.:.|.:|:  ||..:.::.|||..|:..|.:|:...|:||||:::::.
Worm   317 HE------KFDTTKTKFHSGSKTPFIWLSEQKTFVGYENAESLKHKVDYIVENNIGGVMIWAIDF 375

  Fly   398 DD----LKNSCS 405
            ||    |.||.:
Worm   376 DDDQGTLLNSAA 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	84/352 (24%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	88/364 (24%)
cht-2	NP_495798.2	Glyco_18	33..376	CDD:214753	84/352 (24%)
		GH18_chitinase-like	35..376	CDD:299167	83/350 (24%)
		ChtBD1_GH18_2	418..469	CDD:211315
		ChtBD1_GH18_2	496..547	CDD:211315
		ChtBD1_GH18_2	567..618	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810