DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cht11 and CTBS

DIOPT Version :9

Sequence 1:NP_572361.1 Gene:Cht11 / 31630 FlyBaseID:FBgn0029913 Length:432 Species:Drosophila melanogaster
Sequence 2:NP_004379.1 Gene:CTBS / 1486 HGNCID:2496 Length:385 Species:Homo sapiens


Alignment Length:364 Identity:81/364 - (22%)
Similarity:133/364 - (36%) Gaps:117/364 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 KVGQRLVCYYASDGTH-----NLSLLDVPGDLCTHINIGPATLDNATIVLPDTLRQVLQNDTRSF 123
            |....|:||..|.|..     ::||.|:         |.||                       |
Human    86 KYDSELMCYAHSKGARVVLKGDVSLKDI---------IDPA-----------------------F 118

  Fly   124 RAAHPQVHLLLWIGGADSGRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWE-----FPS 183
            ||:        ||.                 :||.|...:       .:|||::|.|     ...
Human   119 RAS--------WIA-----------------QKLNLAKTQ-------YMDGINIDIEQEVNCLSP 151

  Fly   184 AYDRERMHLSQLLYEIRTEWRREKRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFH 248
            .||.    |:.|:.|....:.||...:.:......:|:.|....|:...|....|::.:||||..
Human   152 EYDA----LTALVKETTDSFHREIEGSQVTFDVAWSPKNIDRRCYNYTGIADACDFLFVMSYDEQ 212

  Fly   249 FYREDTPFTGLNAPLYARSQERSLMATFNINYT-VQWWLKSGLEPQRLVVGLPTYGHSFTLVNPL 312
            ...........|||             :|...| ...::|..:.|::||:|:|.||:.:|.:|..
Human   213 SQIWSECIAAANAP-------------YNQTLTGYNDYIKMSINPKKLVMGVPWYGYDYTCLNLS 264

  Fly   313 NHRI---------GAPAS-GYGKCGQLGFTTLTETCECVTKFFKPNLSYDAESCSPYLSAL---- 363
            ...:         |||.| ..|:  |:.:.|:.:.   :......|| :|.:..:||.:..    
Human   265 EDHVCTIAKVPFRGAPCSDAAGR--QVPYKTIMKQ---INSSISGNL-WDKDQRAPYYNYKDPAG 323

  Fly   364 ---QEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDD 399
               |.|  |:|..||:.||.|:::..|.|:.:::.|..|
Human   324 HFHQVW--YDNPQSISLKATYIQNYRLRGIGMWNANCLD 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cht11NP_572361.1 Glyco_18 68..398 CDD:214753 79/357 (22%)
GH18_chitinase-like 69..428 CDD:299167 80/359 (22%)
CTBSNP_004379.1 GH18_chitobiase 39..378 CDD:119354 81/364 (22%)
Glyco_18 <115..358 CDD:214753 69/322 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3325
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D826687at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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