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Protein Alignment Cht11 and CHI3L2

DIOPT Version :9

Sequence 1:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_003991.2	Gene:	CHI3L2 / 1117	HGNCID:	1933	Length:	390	Species:	Homo sapiens

Alignment Length:	392	Identity:	118/392 - (30%)
Similarity:	202/392 - (51%)	Gaps:	45/392 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LLGIQTGEVHKVGQRLVCYYASDGTHNLSLLDVPGD---------LCTHINIGPATLDNATIVLP 109
            ||.:|.|..:|    ||||:.:.....    ..||.         ||:|:....|:::|..:::.
Human    18 LLLLQGGSAYK----LVCYFTNWSQDR----QEPGKFTPENIDPFLCSHLIYSFASIENNKVIIK 74

  Fly   110 DTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSG-RSFALMVANHAMRKLFLRSLREILRTYPSLD 173
            |....:|.....|.:..:|::.:||.|||...| :.|..||.:...|..|:.|:...||.: :.|
Human    75 DKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNH-NFD 138

  Fly   174 GIDLDWEFPSAYDRERMHLSQLLYEIRTEWRRE--KRTND--ILSLAVAAPEGIAFYAYDIREIN 234
            |:|:.|.:|.  .:|..|.:.|::|:...::::  |.|.:  :|:..|:|...:...:|.:.::.
Human   139 GLDVSWIYPD--QKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLA 201

  Fly   235 LYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGL 299
            ...|::||:|:|||...|....||.|:||....|:|...:.:|:.|.|.:|:..|:..:::|:|:
Human   202 KDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGI 266

  Fly   300 PTYGHSFTLVNPLNHRIGAPASGYGKCGQL----GFTTLTETCECVTKFFK-PNLSYDAESCSPY 359
            |||||||||.: ....:||||||.|..|.:    ||....|.|:    |.| ..::...:...||
Human   267 PTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQ----FLKGAKITRLQDQQVPY 326

  Fly   360 LSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLK-NSCSIMPNLKYSEKPVFPLTQA 423
            .....:|:.|::..|:..|..::|:|||||.|::|::.||.. .||:..|         :||.||
Human   327 AVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGP---------YPLVQA 382

  Fly   424 IK 425
            :|
Human   383 VK 384

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.