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Protein Alignment CG14435 and ZNRF1

DIOPT Version :9

Sequence 1:	NP_001162682.2	Gene:	CG14435 / 31628	FlyBaseID:	FBgn0029911	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_115644.1	Gene:	ZNRF1 / 84937	HGNCID:	18452	Length:	227	Species:	Homo sapiens

Alignment Length:	239	Identity:	104/239 - (43%)
Similarity:	127/239 - (53%)	Gaps:	44/239 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 ARSLSSVPDIQQQAQQQQQQGSITSSGSSPHSHPHAAHGHPAVGV-TVSVSGNANANSNSNFTAA 152
            |||....|.:      .....::...|.:|| ..|...|..|:|: :.|||..|....:.: ||.
Human     9 ARSRGPFPGV------STDDSAVPPPGGAPH-FGHYRTGGGAMGLRSRSVSSVAGMGMDPS-TAG 65

  Fly   153 GNNNGSAMQSYMQQRRTLGDSIRDMSMTGGSIAESIALAASATSANGIG---------------- 201
            |...|    .|....|..|||.|... .|||       |:.:|.|:|.|
Human    66 GVPFG----LYTPASRGTGDSERAPG-GGGS-------ASDSTYAHGNGYQETGGGHHRDGMLYL 118

  Fly   202 --RVYTATSLPSHI---W--SFNGIKCPVCNKFVLPDDIECHLVMCLTKPRLSYNEDVLSDAKGE 259
              |...|.:||.||   |  |.:|.|||:|:|.|..|::|.|.:|||:|||||||:|||:...||
Human   119 GSRASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGE 183

  Fly   260 CVICLEDLSPGDTIARLPCLCIYHKGCIDRWFEVNRSCPEHPGD 303
            ||||||:|..|||||||||||||||.|||.||||||||||||.|
Human   184 CVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD 227

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.