DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14435 and znrf2b

DIOPT Version :9

Sequence 1:	NP_001162682.2	Gene:	CG14435 / 31628	FlyBaseID:	FBgn0029911	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_001070196.1	Gene:	znrf2b / 767761	ZFINID:	ZDB-GENE-060929-24	Length:	217	Species:	Danio rerio

Alignment Length:	216	Identity:	102/216 - (47%)
Similarity:	124/216 - (57%)	Gaps:	32/216 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 SSP--HSHPHAAHGHPAVGVTVSVSGNA-------NANSNSNFTAAGNNNGS---AMQSYMQQRR 168
            |||  :....|..|......|.||:|..       |:...|..|:|.:.:.|   |.|....:.|
Zfish     6 SSPAANGRTRAYSGSDLPSATASVNGRTAAVLRYNNSQGASGATSAASASSSAAVASQFISSRTR 70

  Fly   169 TLGDSIRDMSMTGGSIAESIALAASATSAN--------------GIGRVYTATSLPSHI--WSFN 217
            ::|.|.|..|  |.:|..|.|. :||.|.|              |..|:... |||:|:  ..|.
Zfish    71 SVGPSARPQS--GINIPNSGAY-SSADSGNSTPEEPGGERERSTGAPRLVIG-SLPAHLSPHLFG 131

  Fly   218 GIKCPVCNKFVLPDDIECHLVMCLTKPRLSYNEDVLSDAKGECVICLEDLSPGDTIARLPCLCIY 282
            |.|||||:||:..|:::.||||||||||::|||||||...|||.||||:|..|||||||||||||
Zfish   132 GFKCPVCSKFISSDEMDLHLVMCLTKPRVTYNEDVLSKDAGECAICLEELLQGDTIARLPCLCIY 196

  Fly   283 HKGCIDRWFEVNRSCPEHPGD 303
            ||||||.||||||||||||.|
Zfish   197 HKGCIDEWFEVNRSCPEHPAD 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14435	NP_001162682.2	zf-RING_2	258..298	CDD:290367	34/39 (87%)
znrf2b	NP_001070196.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		5/20 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..111		14/50 (28%)
		zf-RING_2	172..212	CDD:290367	34/39 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586864
Domainoid	1	1.000	85	1.000	Domainoid score	I8122
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	167	1.000	Inparanoid score	I4147
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1256682at2759
OrthoFinder	1	1.000	-	-		FOG0001965
OrthoInspector	1	1.000	-	-		otm25539
orthoMCL	1	0.900	-	-		OOG6_105431
Panther	1	1.100	-	-	LDO	PTHR46661
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4296
SonicParanoid	1	1.000	-	-		X146
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.930