Protein Alignment CG14435 and Rnf149

DIOPT Version :10

• Sequence 1: NP_572359.2
• Gene: CG14435 / 31628
• FlyBaseID: FBgn0029911
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_001028307.2
• Gene: Rnf149 / 67702
• MGIID: 2677438
• Length: 394
• Species: Mus musculus
• Alignment Length: 305
• Identity: 64/305 - (20%)
• Similarity: 103/305 - (33%)
• Gaps: 87/305 - (28%)

  Fly    52 GGGGGNDTTGQGFNLLRTLPGLQVYHNQNSTS-IDRQRARSLSSVPD---IQQQAQQQQQQGSI- 111
            |.|||               .|:.|....|.. :|.|...::.||.:   ..:.:.::::||.:
Mouse    28 GVGGG---------------ALEWYSAMVSIEYVDPQSNLTVWSVSESGRFGESSLREERQGLVG 77

  Fly   112 ------TSSGSSPHSH---PHAAHGHPAVG------------VTVSVSGNA------NANSNSNF 149
                  .:.|.:|.:.   |.|....|.|.            |..:...||      |..||.|.
Mouse    78 VPRAPAPAEGCAPDTRFVAPGALGNAPWVALVARGGCTFKDKVLAAARRNASAVVVYNLESNGNA 142

  Fly   150 TAAGNNNGSA-----MQSYMQQRRTLGDSIRDMSMTGGSIAESIALAA-------SATSANGIGR 202
            |...::.|:.     |.||.:     |..|.|:...|..:...|.:..       |..|...:..
Mouse   143 TEPMSHAGTGNIVVIMISYPK-----GREIFDLVQKGIPVKMRIEIGTRHMQEFISGQSVVFVAI 202

  Fly   203 VYTATSLPSHIW---------SFNGIKCPVCN-----KFVLPDDIECHLVMCLTKPRLSYNEDVL 253
            .:....:.|..|         .:.|.:....|     |.|: ..:..|.|        .:.|..:
Mouse   203 AFITMMIISLAWLIFYYIQRFLYTGSQFGSQNHRKETKKVI-GQLPLHTV--------KHGEKGI 258

  Fly   254 SDAKGECVICLEDLSPGDTIARLPCLCIYHKGCIDRWFEVNRSCP 298
            ......|.:|:|:....|.|..|||..|:|:.|||.|...:|:||
Mouse   259 DVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCP 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14435	NP_572359.2	mRING-CH-C4HC2H_ZNRF2	248..303	CDD:438356	18/51 (35%)
Rnf149	NP_001028307.2	PA_GRAIL_like	45..181	CDD:239037	28/140 (20%)
		RING-H2_RNF149	264..311	CDD:438455	17/40 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..394