DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14435 and Y71F9AL.10

DIOPT Version :9

Sequence 1:	NP_001162682.2	Gene:	CG14435 / 31628	FlyBaseID:	FBgn0029911	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_491059.2	Gene:	Y71F9AL.10 / 171852	WormBaseID:	WBGene00022115	Length:	189	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	82/222 - (36%)
Similarity:	114/222 - (51%)	Gaps:	39/222 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 TSIDRQRARSLSSVPDIQQQAQQQQQQGSITSSGSSPHSHPHAAHGHPAVGVTVSVSGNANANSN 146
            :|:..:|.|| :||...|.:.             ||.||....|:...|.....::......:|:
Worm     6 SSVTEERPRS-NSVDTAQVRV-------------SSQHSSSQRANVMTAAEFMQTMRNARFLSSS 56

  Fly   147 SNFTAAGNNNGSAMQSYMQQRRTLGDSIRDMSMTGGSIAESIALAASATSANGIGRVYTATSLPS 211
            |:..|:.::.|.:..:      |.|:..|.:..|.|.:...                ::..|:|.
Worm    57 SDSNASEDDAGPSHST------THGNRSRGLHATPGRLHGH----------------HSRRSVPV 99

  Fly   212 HIWSFNGIKCPVCNKFVLPDDIECHLVMCLTKPRLSYNEDVLSDAKGECVICLEDLSPGDTIARL 276
            .:..   :|||||:|.|..||.:.|||||||:|:::||:|||.|.||||.||||||..|..||||
Worm   100 FMMD---MKCPVCHKVVPSDDADIHLVMCLTRPKITYNDDVLKDDKGECSICLEDLEAGHKIARL 161

  Fly   277 PCLCIYHKGCIDRWFEVNRSCPEHPGD 303
            ||||||||.|||.||:....|||||||
Worm   162 PCLCIYHKQCIDDWFKRKNCCPEHPGD 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14435	NP_001162682.2	zf-RING_2	258..298	CDD:290367	27/39 (69%)
Y71F9AL.10	NP_491059.2	mRING-CH-C4HC2H_ZNRF	144..186	CDD:319403	29/41 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162465
Domainoid	1	1.000	67	1.000	Domainoid score	I6491
eggNOG	1	0.900	-	-		E1_KOG0801
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1638
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1256682at2759
OrthoFinder	1	1.000	-	-		FOG0001965
OrthoInspector	1	1.000	-	-		oto17458
orthoMCL	1	0.900	-	-		OOG6_105431
Panther	1	1.100	-	-	LDO	PTHR46661
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4296
SonicParanoid	1	1.000	-	-		X146
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.730