DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14435 and RNF133

DIOPT Version :10

Sequence 1:	NP_572359.2	Gene:	CG14435 / 31628	FlyBaseID:	FBgn0029911	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_631914.1	Gene:	RNF133 / 168433	HGNCID:	21154	Length:	376	Species:	Homo sapiens

Alignment Length:	39	Identity:	17/39 - (43%)
Similarity:	21/39 - (53%)	Gaps:	0/39 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 CVICLEDLSPGDTIARLPCLCIYHKGCIDRWFEVNRSCP 298
            ||||.|...|.|.:..|.|...:||.|||.|...:.:||
Human   256 CVICFERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14435	NP_572359.2	mRING-CH-C4HC2H_ZNRF2	248..303	CDD:438356	17/39 (44%)
RNF133	NP_631914.1	PA_GRAIL_like	43..177	CDD:239037
		RING-H2_RNF128-like	254..302	CDD:438454	17/39 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..376
Blue background indicates that the domain is not in the aligned region.

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