Protein Alignment CG14435 and TRAIP

DIOPT Version :10

• Sequence 1: NP_572359.2
• Gene: CG14435 / 31628
• FlyBaseID: FBgn0029911
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_005870.2
• Gene: TRAIP / 10293
• HGNCID: 30764
• Length: 469
• Species: Homo sapiens
• Alignment Length: 42
• Identity: 13/42 - (30%)
• Similarity: 22/42 - (52%)
• Gaps: 2/42 - (4%)

  Fly   260 CVICLEDLSPGDTIARLPCLCIYHKGCIDRWFEV--NRSCPE 299
            |.||.:.......:|.:.|...:|..|:.:|||.  :|:||:
Human     7 CTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQ 48

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14435	NP_572359.2	mRING-CH-C4HC2H_ZNRF2	248..303	CDD:438356	13/42 (31%)
TRAIP	NP_005870.2	RING-H2_TRAIP	6..50	CDD:438143	13/42 (31%)
		EnvC	65..>278	CDD:443969
		Interaction with CYLD. /evidence=ECO:0000269|PubMed:14676304	211..469
		PIP-box. /evidence=ECO:0000269|PubMed:26711499	460..469