Protein Alignment mAChR-C and taar10b

DIOPT Version :10

• Sequence 1: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001076372.1
• Gene: taar10b / 794579
• ZFINID: ZDB-GENE-041014-67
• Length: 336
• Species: Danio rerio
• Alignment Length: 350
• Identity: 90/350 - (25%)
• Similarity: 145/350 - (41%)
• Gaps: 63/350 - (18%)

  Fly     6 SSSPAWDYRSSPEALGVVPFL-WQHQNATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNI 69
            |.:..||          .||| ::..|.:.......|:...|     |::..:|...:.|: ||:
Zfish     8 SHNGIWD----------KPFLCYEFSNRSCQKFVYPLETRIF-----LYILFSASSIITII-GNL 56

  Fly    70 LTIVAVRTCRHLRSVISNLFILSLAVSDFCV-GLALPYHLV------FYMGSDIGAMRGPCLLRF 127
            |.|:.|...|.|.:. :|..||||||:|..| |:.:|..::      :|:|...      |.:..
Zfish    57 LVIITVVHFRQLHTP-TNYLILSLAVADLLVGGVVMPPSMLRSIETCWYLGDLF------CKIHS 114

  Fly   128 FLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFW---- 188
            .|.:..|..|:|.|..|::|||.|:.:...|...||......:||..|.:.|::....:|.
Zfish   115 SLDVTLCTASILNLCIISLDRYYAICHPFQYHSKMTSLATLVMIIICWTVSAVLGFGMIFMELNI 179

  Fly   189 ---------NRWPDAQACEFD--EVLAPGYIAGVITPGFVIIWICMFLVYWRIMREASKQALRLR 242
                     |...:.:...|.  ||.....:|....|.||     |..||.:|:.||.:|...:
Zfish   180 LGVEDFYYENVDCNGRCLVFQSREVAVFMSLACFYIPAFV-----MLCVYLKILHEAQRQVQAI- 238

  Fly   243 QSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTF 307
            |||           |..|..:.|:.:.:..|:|.|...|:|:|...:...|.......:::....
Zfish   239 QSV-----------NSELKKEGKATKTLAIIVGVFLTFWIPFFLCNLIDPFIGYSVPPLLFDLFL 292

  Fly   308 SLAIANSALNPIIYSWKNSGFRRAF 332
            .:...||..|||:|::..|.||.||
Zfish   293 WVGYYNSTCNPIVYAFFYSWFRHAF 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	75/293 (26%)
		TM helix 1	53..78	CDD:410626	7/24 (29%)
		TM helix 2	86..111	CDD:410626	11/31 (35%)
		TM helix 3	123..153	CDD:410626	11/29 (38%)
		TM helix 4	166..185	CDD:410626	4/18 (22%)
		TM helix 5	204..229	CDD:410626	7/24 (29%)
		TM helix 6	261..291	CDD:410626	7/29 (24%)
		TM helix 7	300..325	CDD:410626	6/24 (25%)
taar10b	NP_001076372.1	7tmA_TAAR1	38..317	CDD:320438	80/308 (26%)
		TM helix 1	39..65	CDD:320438	9/31 (29%)
		TM helix 2	72..98	CDD:320438	11/25 (44%)
		TM helix 3	110..140	CDD:320438	11/29 (38%)
		TM helix 4	152..175	CDD:320438	4/22 (18%)
		TM helix 5	201..230	CDD:320438	10/33 (30%)
		TM helix 6	246..276	CDD:320438	7/29 (24%)
		TM helix 7	285..310	CDD:320438	6/24 (25%)